Aim We investigated the ability of prototypical inflammatory cytokines to predict clinical
outcomes in a large population of patients with chronic systolic heart failure (HF). Methods …

Background Several cytokines are associated with the development and/or progression of
chronic heart failure (CHF). Our aim was to look more closely at the cytokine networks …

In the infarcted heart, the damage‐associated molecular pattern proteins released by
necrotic cells trigger both myocardial and systemic inflammatory responses. Induction of …

Background—Previous reports have shown that elevated circulating levels of cytokines
and/or cytokine receptors predict adverse outcomes in patients with heart failure. However …

Acute myocardial infarction is the leading cause of morbidity and mortality in the adult
population of developed and developing nations. Although the prompt restoration of …

Recent studies have identified the importance of proinflammatory mediators in the
development and progression of heart failure. The growing appreciation of the …

The mammalian heart contains a population of resident macrophages that expands in
response to injury through the recruitment of circulating monocytes (1). After myocardial …

This editorial refers to 'Effect of a single dose of the interleukin-6 receptor antagonist
tocilizumab on inflammation and troponin T release in patients with non-ST elevation …

Mediators of myocardial inflammation, predominantly cytokines, have for many years been
implicated in the healing processes after infarction. In recent years, however, more attention …

Aims Numerous anti-inflammatory drugs have been tested in large animal studies of
myocardial infarction (MI). Despite positive results, translation of anti-inflammatory strategies …