For a long time, cardiovascular clinicians have focused their research on coronary
atherosclerotic cardiovascular disease and acute myocardial infarction due to their high …

Persistent inflammation, involving increased levels of inflammatory cytokines, seems to play
a pathogenic role in chronic heart failure (HF) by influencing heart contractility, inducing …

Despite considerable progress over the last decades, acute myocardial infarction continues
to remain the major cause of morbidity and mortality worldwide. The present therapies …

The immune system is a system of dynamic equilibrium, with inflammatory responses
(mediated by T helper type 1 cells, interleukin [IL]-1β, interferon-γ, and tumor necrosis factor …

Cytokines and their receptors have numerous physiological functions. Altered
concentrations of these mediators are associated with various afflictions. For example, over …

Inflammatory response and cytokine elaboration are particularly active after myocardial
infarction and contribute to cardiac remodeling and eventual host outcome. The triggers of …

There is substantial evidence of immune modulation promoting the downregulation of
inflammatory cytokines thus increasing several important and potentially therapeutic anti …

Cytokines have been associated with the pathogenesis of acute coronary syndromes and
chronic heart failure (CHF), which are both associated with cardiomyocyte loss. In CHF …

Aim To evaluate the effect of interleukin-6 inhibition with tocilizumab on the cytokine network
in patients with acute non-ST-elevation myocardial infarction (NSTEMI). Methods 117 …

Abstract Purpose of Review This review aims to summarize the role of the interleukin-1 (IL-1)
blocking agents in cardiovascular diseases, briefly describing the pathogenetic rationale …