The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases
J Zhen, Z Zhou, M He, HX Han, EH Lv… - Frontiers in …, 2023 - frontiersin.org
Morbidity and mortality of cardiovascular diseases (CVDs) are exceedingly high worldwide.
Researchers have found that the occurrence and development of CVDs are closely related …
Researchers have found that the occurrence and development of CVDs are closely related …
Trimethylamine/trimethylamine-N-oxide as a key between diet and cardiovascular diseases
S He, H Jiang, C Zhuo, W Jiang - Cardiovascular Toxicology, 2021 - Springer
Trimethylamine (TMA) is a gut microbiota-derived metabolite which comes from diets rich of
choline, betaine or l-carnitine and could be further converted to Trimethylamine-N-oxide …
choline, betaine or l-carnitine and could be further converted to Trimethylamine-N-oxide …
Microbiome, trimethylamine N-oxide, and cardiometabolic disease
There is increasing appreciation that changes in microbiome composition and function can
promote long-term susceptibility for cardiometabolic risk. Gut microbe-derived metabolites …
promote long-term susceptibility for cardiometabolic risk. Gut microbe-derived metabolites …
Gut microbiota-derived TMAO: a causal factor promoting atherosclerotic cardiovascular disease?
M Canyelles, C Borràs, N Rotllan, M Tondo… - International journal of …, 2023 - mdpi.com
Trimethylamine-N-oxide (TMAO) is the main diet-induced metabolite produced by the gut
microbiota, and it is mainly eliminated through renal excretion. TMAO has been correlated …
microbiota, and it is mainly eliminated through renal excretion. TMAO has been correlated …
Trimethylamine N-Oxide, the Microbiome, and Heart and Kidney Disease
Trimethylamine N-oxide (TMAO) is a biologically active molecule and is a putative promoter
of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its …
of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its …
Trimethylamine N-Oxide: A Link among Diet, Gut Microbiota, Gene Regulation of Liver and Intestine Cholesterol Homeostasis and HDL Function
M Canyelles, M Tondo, L Cedó, M Farràs… - International journal of …, 2018 - mdpi.com
Recent evidence, including massive gene-expression analysis and a wide-variety of other
multi-omics approaches, demonstrates an interplay between gut microbiota and the …
multi-omics approaches, demonstrates an interplay between gut microbiota and the …
Gut metabolite trimethylamine-N-oxide in atherosclerosis: from mechanism to therapy
BY Wang, J Qiu, JF Lian, X Yang… - Frontiers in cardiovascular …, 2021 - frontiersin.org
Atherosclerosis is associated with various pathological manifestations, such as ischemic
heart disease, ischemic stroke, and peripheral arterial disease, and remains a leading …
heart disease, ischemic stroke, and peripheral arterial disease, and remains a leading …
The role of microbiota in cardiovascular risk: focus on trimethylamine oxide
H Al-Rubaye, G Perfetti, JC Kaski - Current Problems in Cardiology, 2019 - Elsevier
The extensive collection of bacteria cohabiting within the host collaborates with human
functions and metabolisms in both health and disease. The fine equilibrium of commensals …
functions and metabolisms in both health and disease. The fine equilibrium of commensals …
Gut-derived metabolite, trimethylamine-N-oxide (TMAO) in cardio-metabolic diseases: detection, mechanism, and potential therapeutics
Trimethylamine N-oxide (TMAO) is a biologically active gut microbiome-derived dietary
metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely …
metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely …
Gut microbiota-derived trimethylamine-N-oxide: A bridge between dietary fatty acid and cardiovascular disease?
M He, CP Tan, YJ Xu, Y Liu - Food Research International, 2020 - Elsevier
Cardiovascular disease (CVD) is a serious disease that endangers human health and is one
of the leading causes of death. Recent studies have reported that gut microbiota plays an …
of the leading causes of death. Recent studies have reported that gut microbiota plays an …
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