The cell walls of fungi are critical for cellular structure and rigidity but also serve as a major
communicator to alert the cell to the changing environment. In response to stresses …

A common feature shared by systemic fungal pathogens of environmental origin, such as
Cryptococcus neoformans, is their ability to adapt to mammalian core body temperature. In …

Infectious microorganisms often play a role in modulating the immune responses of their
infected hosts. We demonstrate that Cryptococcus neoformans signals through the Rim101 …

The polysaccharide capsule of Cryptococcus neoformans—an opportunistic basidiomycete
pathogen and the major etiological agent of fungal meningoencephalitis—is a key virulence …

The interactions between a host and microbe drive the health and disease status of the host.
Of importance is the cause of dysbiosis in the presence of a pathogen, and critically, the …

Cryptococcus neoformans is a ubiquitous environmental fungus capable of establishing an
infection in a human host. Rapid changes in environments and exposure to the host immune …

As they proliferate, fungi expose antigens at their cell surface that are potent stimulators of
the innate immune response, and yet the commensal fungus Candida albicans is able to …

Cryptococcus neoformans is one of the few environmental fungi that can survive within a
mammalian host and cause disease. Although many of the factors responsible for …

Cryptococcus neoformans is an opportunistic fungal pathogen with a polysaccharide
capsule that becomes greatly enlarged in the mammalian host and during in vitro growth in …

The yeast-to-hypha transition is tightly associated with pathogenicity in many human
pathogenic fungi, such as the model fungal pathogen Cryptococcus neoformans, which is …