Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

Out of their niche environment, adult stem cells, such as mesenchymal stem cells (MSCs),
spontaneously differentiate. This makes both studying these important regenerative cells …

Numerous studies have demonstrated that the differentiation potential of human
mesenchymal stem cells (hMSCs) can be modulated by chemical and physical cues. In 2D …

Background Human mesenchymal stem cells (hMSCs) are, due to their pluripotency, useful
sources of cells for stem cell therapy and tissue regeneration. The phenotypes of hMSCs are …

Interaction between adherent cells and extracellular matrix/scaffold surface features
performs a crucial role in inducing physiological functions via signal transduction …

Stem cells (SCs) can self-renew or differentiate into different cell types, which makes them
an ideal cell source for therapies based on tissue engineering. Despite these characteristics …

Mesenchymal stem cells (MSCs) have huge potential to be used in cell therapies because of
their pluripotency and immunoregulatory attributes. To harness and maximize the …

Using the material technique recently developed by us, we prepared a micropattern on poly
(ethylene glycol)(PEG) hydrogel to keep background resistant to cell adhesion for a long …

Recent regenerative medicine and tissue engineering strategies (using cells, scaffolds,
medical devices and gene therapy) have led to fascinating progress of translation of basic …

Signals from the microenvironment around a cell are known to influence cell behavior.
Material properties, such as biochemical composition and substrate stiffness, are today …