Peptide-based therapeutics for oncology

E Fisher, K Pavlenko, A Vlasov… - Pharmaceutical Medicine, 2019 - Springer
The development of peptide-based drugs, which are usually synthetic analogues of
endogenous peptides, is currently one of the most topical directions in drug development …

Recent developments in peptide-based cancer therapeutics.

A Sehgal - Current Opinion in Drug Discovery & Development, 2002 - europepmc.org
Peptides make up only a fraction of therapeutically beneficial pharmaceutical molecules that
are either in clinical testing or in the market. Despite the initially low number and impact of …

The potential use of peptides in cancer treatment

B Yavari, R Mahjub, M Saidijam… - Current Protein and …, 2018 - ingentaconnect.com
Conventional chemotherapeutic drugs have significant limitations. For example, tumors may
develop resistance, cancers may relapse after treatment, and the drugs may induce …

The future of peptides in cancer treatment

K Kurrikoff, D Aphkhazava, Ü Langel - Current Opinion in Pharmacology, 2019 - Elsevier
Highlights•Peptides from three distinct groups are important for cancer therapy and
diagnostics.•Anticancer peptides are most frequently mimics of natural proteins and …

Peptide-based cancer therapy: opportunity and challenge

D Wu, Y Gao, Y Qi, L Chen, Y Ma, Y Li - Cancer letters, 2014 - Elsevier
Cancer is one of the leading causes of death worldwide. Conventional cancer therapies
mainly focus on mass cell killing without high specificity and often cause severe side effects …

Recent advances in peptide-based approaches for cancer treatment

AC Conibear, A Schmid, M Kamalov… - Current Medicinal …, 2020 - ingentaconnect.com
Background: Peptide-based pharmaceuticals have recently experienced a renaissance due
to their ability to fill the gap between the two main classes of available drugs, small …

Anti-cancer peptides: Their current trends in the development of peptide-based therapy and anti-tumor drugs

A Lath, AR Santal, N Kaur, P Kumari… - Biotechnology and …, 2023 - Taylor & Francis
Human cancer remains a cause of high mortality throughout the world. The conventional
methods and therapies currently employed for treatment are followed by moderate-to-severe …

[HTML][HTML] Evolving strategies and application of proteins and peptide therapeutics in cancer treatment

AG Mukherjee, UR Wanjari, AV Gopalakrishnan… - Biomedicine & …, 2023 - Elsevier
Several proteins and peptides have therapeutic potential and can be used for cancer
therapy. By binding to cell surface receptors and other indicators uniquely linked with or …

[HTML][HTML] Novel peptide therapeutic approaches for cancer treatment

CM Li, P Haratipour, RG Lingeman, JJP Perry, L Gu… - Cells, 2021 - mdpi.com
Peptides are increasingly being developed for use as therapeutics to treat many ailments,
including cancer. Therapeutic peptides have the advantages of target specificity and low …

[HTML][HTML] Anti-cancer peptide-based therapeutic strategies in solid tumors

M Karami Fath, K Babakhaniyan, M Zokaei… - Cellular & Molecular …, 2022 - Springer
Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …