The incidence of diabetes and its associated micro-and macrovascular complications is
greatly increasing worldwide. The most prevalent vascular complications of both type 1 and …

Macrovascular complications such as atherosclerosis, myocardial infarction and stroke, and
microvascular complications such as nephropathy, retinopathy, and neuropathy are the …

Diabetes is associated with significantly accelerated rates of several debilitating
microvascular complications such as nephropathy, retinopathy, and neuropathy, and …

Increasing evidence suggests that epigenetic factors might regulate the complex interplay
between genes and the environment, and affect human diseases, such as diabetes and its …

Diabetes mellitus (type 1 and type 2) and the complications associated with this condition
are an urgent public health problem, as the incidence of diabetes mellitus is steadily …

There has been a rapid increase in the incidence of diabetes as well the associated
vascular complications. Both genetic and environmental factors have been implicated in …

Recent estimates indicate that diabetes mellitus currently affects more than 10% of the
world's population. Evidence from both the laboratory and large scale clinical trials has …

The development and progression of diabetic kidney disease (DKD), a highly prevalent
complication of diabetes mellitus, are influenced by both genetic and environmental factors …

There is growing evidence that epigenetic regulation of gene expression including post-
translational histone modifications (PTHMs), DNA methylation and microRNA (miRNA) …

Epigenetic modifications regulate critical functions that underlie chromosome metabolism.
Understanding the molecular changes to chromatin structure and the functional relationship …