Midazolam is one of many bitter drugs where provision of a suitable oral paediatric
formulation, particularly in the pre‐anaesthetic setting, remains a challenge. To overcome …

In this study, the authors evaluate the pharmacodynamics, safety, and acceptability of a new
cherry‐flavored oral syrup formulation of midazolam. This randomized, double‐blind …

Midazolam is widely used as a preanesthetic medication for children. Prior studies have
used extemporaneous formulations to disguise the bitter taste of IV midazolam and to …

We compared two available oral formulations of midazolam with respect to sedation score
and plasma midazolam levels in pediatric surgical patients 2–10 yr old. The commercially …

Ozalin®, a novel oral solution of 0.2% midazolam, is an effective option for moderate
sedation prior to a therapeutic or diagnostic procedure, and as premedication before …

The question of whether premedication should be routinely used in pediatric patients has
recently been the focus of debate among pediatric anesthetists. Although most of us have …

One of the most widely used options for minimal/moderate sedation in pediatric patients is
oral midazolam, as it presents an alternative to less well‐accepted routes of administration …

Conclusions The pharmacokinetics of midazolam in our patients showed a shorter half-life,
probably due to the higher hepatic clearance based on the high CI in children, as …

Purpose To investigate the tolerability of midazolam intravenous (IV) solution by masking its
bitter taste through the addition of syrup. Methods In the waiting area before surgery at our …

Introduction In the absence of a licensed formulation in many countries worldwide,
ADV6209, an innovative 2 mg/ml oral solution of midazolam containing cyclodextrin, has …