Osthol (osthole), known as a neuroprotective drug, has shown potent anticancer activity.
However, the potential clinical application of osthol is limited due to its low water solubility …

Glioblastoma is a grade IV malignant glioma with high recurrence and metastasis and faces
a therapeutic obstacle that the blood-brain barrier (BBB) severely hinders the brain entry …

Gliomas are one of the prominent cancers of the central nervous system with limited
therapeutic modalities. The present investigation evaluated the synergistic effect of …

Background: Using Multi-Walled Carbon Nanotubes (MWCNTs) as a drug delivery system,
can avoid the need for solvents and preventing drug precipitation in aqueous solution …

Many natural products with greater therapeutic efficacy are limited to target several chronic
diseases such as cancer, diabetes, and neurodegenerative diseases. Among the natural …

Ursolic acid (UA), a pentacyclic triterpenoid and a phytochemical, is a potent inhibitory agent
against proliferation of various tumors. Polyhydroxybutyrate nanoparticles (PHB NPs) are …

Background: Glioblastoma (GBM) is an extremely invasive and heterogenous malignant
brain tumor. Despite advances in current anticancer therapy, treatment options for …

Capsaicin is recognized as a natural tumor preventive compound and exhibits a remarkable
anticancer action. Strong inhibitory role of capsaicin on gliomas has been well documented …

Spearmint oil (SMO), a commonly used essential oil for oral care products, possesses
various interesting functions, especially for anticancer property. However, the application of …

The encapsulation of hydrophilic drugs is still a challenge due to their tendency to leak into
the outer aqueous phase. The aim of the study is to develop and evaluate Ondansetron HCl …