Plasma P-tau181 and P-tau217 in patients with traumatic encephalopathy syndrome with and without evidence of Alzheimer disease pathology

BM Asken, JA Tanner, L VandeVrede, WG Mantyh… - Neurology, 2022 - AAN Enterprises
Background and Objectives Traumatic encephalopathy syndrome (TES) has overlapping
clinical symptoms with Alzheimer disease (AD). AD pathology commonly co-occurs with …

Cognitive, functional, and neuropsychiatric correlates of regional tau pathology in autopsy-confirmed chronic traumatic encephalopathy

ML Alosco, M White, C Bell, F Faheem… - Molecular …, 2024 - Springer
Background Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease
characterized by hyperphosphorylated tau (p-tau) accumulation. The clinical features …

Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome

BM Asken, JA Tanner, LS Gaynor… - Alzheimer's Research & …, 2023 - Springer
Background Traumatic encephalopathy syndrome (TES) is a clinical phenotype sensitive but
non-specific to underlying chronic traumatic encephalopathy (CTE) neuropathology …

Tau seeding in chronic traumatic encephalopathy parallels disease severity

SK Kaufman, S Svirsky, JD Cherry, AC McKee… - Acta …, 2021 - Springer
Chronic traumatic encephalopathy (CTE), a neurodegenerative tauopathy, is associated
with behavioral, mood and cognitive impairment, including dementia. Tauopathies are …

[HTML][HTML] Repetitive head impact exposure and later-life plasma total tau in former National Football League players

ML Alosco, Y Tripodis, J Jarnagin, CM Baugh… - Alzheimer's & dementia …, 2017 - Elsevier
Introduction Blood protein analysis of total tau (t-tau) may be a practical screening biomarker
for chronic traumatic encephalopathy (CTE), a neurodegenerative tauopathy associated with …

A comparison between tau and amyloid-β cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease

KW Turk, A Geada, VE Alvarez, W Xia… - Alzheimer's Research & …, 2022 - Springer
Background Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic
encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer's …

Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease

SA Stathas, VE Alvarez, W Xia, R Nicks… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy
associated with repetitive head impacts (RHI) typically sustained by contact sport athletes …

Characterizing tau deposition in chronic traumatic encephalopathy (CTE): utility of the McKee CTE staging scheme

ML Alosco, JD Cherry, BR Huber, Y Tripodis… - Acta …, 2020 - Springer
Chronic traumatic encephalopathy (CTE) is a tauopathy associated with repetitive head
impacts (RHI) that has been neuropathologically diagnosed in American football players …

Alzheimer's disease marker phospho-tau181 is not elevated in the first year after moderate-to-severe TBI

N Graham, K Zimmerman, AJ Heslegrave… - Journal of Neurology …, 2024 - jnnp.bmj.com
Background Traumatic brain injury (TBI) is associated with the tauopathies Alzheimer's
disease and chronic traumatic encephalopathy. Advanced immunoassays show significant …

Characterization of early pathological tau conformations and phosphorylation in chronic traumatic encephalopathy

NM Kanaan, K Cox, VE Alvarez, TD Stein… - … of Neuropathology & …, 2016 - academic.oup.com
Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy that develops
after repetitive head injury. Several lines of evidence in other tauopathies suggest that tau …