Atypical antipsychotic drugs were introduced in the early 1990s. Unlike typical
antipsychotics, which are effective only against positive symptoms of schizophrenia, atypical …

Since their first application in psychiatry seventy years ago, antipsychotic drugs, besides
schizophrenia, have been widely used in the treatment of mood disorders. Such an …

Schizophrenia and depression are heterogeneous disorders. The complex
pathomechanism of the diseases imply that medication responses vary across patients …

Serotonin (5-HT) is a monoamine neurotransmitter that plays an important role in
physiological functions. 5-HT has been implicated in sleep, feeding, sexual behavior …

Over the past decade or so, atypical antipsychotic drugs have revolutionized the
pharmacologic treatment of schizophrenia and related disorders. All currently approved …

The introduction of atypical antipsychotics (AAPs) since the discovery of its prototypical drug
clozapine has been a revolutionary pharmacological step for treating psychotic patients as …

The original definition of atypical antipsychotic drugs (APD) was drugs that are effective
against positive symptoms in schizophrenia with no or little extrapyramidal symptoms (EPS) …

Antipsychotics represent the mainstay of schizophrenia pharmacological therapy, and their
role has been expanded in the last years to mood disorders treatment. Although introduced …

Cognitive impairments are considered to largely affect functional outcome in patients with
schizophrenia, other psychotic illnesses, or mood disorders. Specifically, there is much …

Schizophrenia is a debilitating mental illness which involves three groups of symptoms, ie,
positive, negative and cognitive, and has major public health implications. According to …