Purpose Molecular imaging using positron emission tomography (PET) radiotracers targeted
to tumor vasculature offers a noninvasive method for early detection of tumor angiogenesis …

Angiogenesis plays a key role in cancer progression and correlates with disease
aggressiveness and poor clinical outcomes. Affinity ligands discovered by screening phage …

Tumor-associated macrophages (TAMs) are known to promote cancer development and
metastasis. In this study, a TAMs-targeting peptide named M2pep was selected to …

Abstract 64 Cu-cyclam-RAFT-c (-RGDfK-) 4 is a novel multimeric positron emission
tomography (PET) probe for α V β 3 integrin imaging. Its uptake and α V β 3 expression in …

Purpose This study aimed to evaluate the potential of PEGylated dimeric GX1 peptide as a
radiotracer for imaging of colorectal cancer vasculature in a LoVo tumor xenografted mouse …

We have previously labeled cyclic RGD peptide c (RGDyK) with fluorine-18 through
conjugation labeling via a prosthetic 4-[18 F] fluorobenzoyl moiety and applied this [18 F] FB …

So far, there is no satisfactory imaging modality to monitor antiangiogenesis therapy of
ovarian cancer noninvasively. The aim of this study was to evaluate the effectiveness and …

Integrin αvβ3 plays a critical role in tumor-induced angiogenesis and metastasis and has
become a promising diagnostic indicator and therapeutic target for various solid tumors …

Purpose Radiolabeled heterodimeric peptide has emerged as a highly promising targeting
strategy for PET imaging due to their superior properties. RGD and GE11 are two peptides …

Pretargeted PET imaging has emerged as an effective strategy for merging the exquisite
selectivity of antibody-based targeting vectors with the rapid pharmacokinetics of …