Peptides containing asparagine-glycine-arginine (NGR) and arginine-glycine-aspartic acid
(RGD) sequence are being developed for tumor angiogenesis-targeted imaging and …

Angiogenesis is a common feature of many physiological processes and pathological
conditions. RGD-containing peptides can strongly bind to integrin αvβ3 expressed on …

Non-invasive detection of vascular endothelial growth factor receptor 2 (VEGFR2) by
positron emission tomography (PET) would allow the evaluation of tumor vascular activity in …

The αv integrins, which act as cell adhesion molecules, are closely involved with tumor
invasion and angiogenesis. In particular, αvβ3 integrin, which is specifically expressed on …

Radiolabeled cyclic RGD (Arg-Gly-Asp) peptides represent a new class of radiotracers with
potential for early tumor detection and noninvasive monitoring of tumor metastasis and …

Comparison and evaluation of two RGD peptides labelled with 68Ga or 18F for PET imaging
of angiogenesis in animal models of human glioblastoma or lung carcinoma - PMC Back to …

This purpose of this study is to determine the efficacy of a 45-amino acid Gp2 domain,
engineered to bind to epidermal growth factor receptor (EGFR), as a positron emission …

Due to the high mortality of lung cancer, there is a critical need to develop diagnostic
procedures enabling early detection of the disease while at a curable stage. Targeted …

Vascular endothelial growth factor receptor (VEGFR) and integrin αv are over-expressed in
angiogenesis of variety malignant tumors with key roles in angiogenesis, and have been …

Purpose Our goal was to demonstrate that suitably derivatized monomeric RGD peptide-
based PET tracers, targeting integrin α v β 3, may offer advantages in image contrast, time …