Background Meropenem is a carbapenem antibiotic commonly used in critically ill patients
to treat severe infections. The available pharmacokinetic (PK) data has been mostly …

Purpose Patients admitted to intensive care unit (ICU) with Klebsiella pneumoniae infections
are characterized by high mortality. The aims of the present study were to investigate the …

Abstract Background and Objectives Meropenem is frequently used for the treatment of
severe bacterial infections in critically ill patients. Because critically ill patients are more …

Background and objective: Meropenem is a carbapenem antibacterial frequently prescribed
for the treatment of severe infections in critically ill patients, including those receiving …

Background: Meropenem is an effective β-lactam antibiotic that is frequently used to treat
serious infections in both intensive care unit (ICU) and febrile neutropenic …

Several pathophysiological changes can alter meropenem pharmacokinetics in critically ill
patients, thereby increasing the risk of subtherapeutic concentrations and affecting …

Introduction Meropenem is a carbapenem antibiotic, which has demonstrated excellent
antimicrobial activity against gram-negative clinical isolates. It is also commonly used in …

Objective: To test whether a prolonged 3-hour infusion of meropenem 500mg achieves an
equivalent proportion of time above the minimal inhibitory concentration (MIC)(% T MIC) to …

Objectives The use of extended intermittent infusion (EII) or continuous infusion (CI) of
meropenem is recommended in intensive care unit (ICU) patients, but few data comparing …

Purpose To develop a meropenem population pharmacokinetic model in critically ill patients
with particular focus on optimizing dosing regimens based on renal function. Methods …