Extracting dynamical information from single‐cell transcriptomics is a novel task with the
promise to advance our understanding of cell state transition and interactions between …

Alternative mRNA splicing enables a single gene to produce multiple protein products that
are specific to tissue type or developmental stage. Aberrant splicing patterns lead to …

Motivation Alternative splicing and alternative transcription are a major mechanism for
generating transcriptome diversity. Differential alternative splicing and transcription (DAST) …

Alternative splicing (AS) is a highly-regulated post-transcriptional mechanism known to
modulate isoform expression within genes and contribute to cell-type identity. However, the …

Motivation: In eukaryotic cells, alternative splicing expands the diversity of RNA transcripts
and plays an important role in tissue-specific differentiation, and can be misregulated in …

Motivation As more and larger genomics studies appear, there is a growing need for
comprehensive and queryable cross-study summaries. These enable researchers to …

Motivation Alternative splicing removes intronic sequences from pre-mRNAs in alternative
ways to produce different forms (isoforms) of mature mRNA. The composition of expressed …

Alternative splicing plays an essential role in many cellular processes and bears major
relevance in the understanding of multiple diseases, including cancer. High-throughput RNA …

Alternative splicing is widely acknowledged to be a crucial regulator of gene expression and
is a key contributor to both normal developmental processes and disease states. While cost …

For many years, array‐based methods have been used successfully to interrogate the
transcriptome of the cell. These methods rely on quantification of the hybridization intensity …