Background The increase in detections of Plasmodium vivax infection in Duffy-negative
individuals in Africa has challenged the dogma establishing the unique P. vivax Duffy …

Background Plasmodium vivax infection is known to be rare in West/Central Africa, the most
accepted explanation being the lack of expression of erythroid Duffy antigen in the local …

Background Duffy blood group polymorphisms are important in areas where Plasmodium
vivax is present because this surface antigen is thought to act as a key receptor for this …

Background The interaction between the Plasmodium vivax Duffy-binding protein and the
corresponding Duffy Antigen Receptor for Chemokines (DARC) is primarily responsible for …

Objectives Plasmodium vivax malaria was thought to be rare in Africans who lack the Duffy
blood group antigen expression. However, recent studies indicate that P. vivax can infect …

Negative Duffy expression on the surface of human red blood cells was believed to be a
barrier for Plasmodium vivax infection in most Africans. However, P. vivax has been …

Background Malaria is a significant public health concern in Haiti where approximately
30,000 cases are reported annually with CDC estimates as high as 200,000. Malaria …

The Duffy protein, a transmembrane molecule, functions as a receptor for various
chemokines and facilitates attachment between the reticulocyte and the Plasmodium Duffy …

Background Recent studies from different malaria-endemic regions including western Africa
have now shown that Plasmodium vivax can infect red blood cells (RBCs) and cause clinical …

Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …