Effects of nebulizer fill volume on the efficacy and safety of the bronchodilator

H Saeed, H Rabea, NS Abdelwahab… - Journal of Drug Delivery …, 2020 - Elsevier
This study aimed to demonstrate the effect of adding saline to the respirable-solution of
salbutamol placed in a nebulization chamber on the clinical status of the ventilated patient. A …

Salbutamol output from two jet nebulizers

SA Langford, MB Allen - Respiratory medicine, 1993 - Elsevier
Nebulized bronchodilators are commonly used in the management of patients with airflow
obstruction, although there is little information available on the bronchodilator output from …

Enhanced delivery of nebulised salbutamol during non‐invasive ventilation

LD Calvert, JM Jackson, JA White… - Journal of pharmacy …, 2006 - Wiley Online Library
Non‐invasive ventilation (NIV) is used to treat acute respiratory failure. Nebulised drugs can
be delivered concurrently with NIV or during breaks from ventilatory support. We …

Nebuliser performance, pharmacokinetics, airways and systemic effects of salbutamol given via a novel nebuliser delivery system (" Ventstream").

DM Newnham, BJ Lipworth - Thorax, 1994 - thorax.bmj.com
BACKGROUND--Currently available nebulisers are inefficient and show variable aerosol
deposition in the lung owing to the differences in the particle size generated. The aim of this …

Changes in salbutamol concentration in the reservoir solution of a jet nebulizer

JA Wood, RSE Wilson, C Bray - British journal of diseases of the chest, 1986 - Elsevier
An increase in concentration of salt in the reservoir solution of jet nebulizers driven by dry
compressed gas has been observed but changes in salbutamol concentration have not …

Mass balance of nebulized drug delivery: Residual drug levels and the effects of an alternative air humidification method

BA Filas, CS Lengsfeld - Atomization and Sprays, 2008 - dl.begellhouse.com
Pulmonary drug delivery through the use of in-line nebulizers is a widespread method for
delivering therapeutics to mechanically ventilated patients. However, previous studies have …

Comparison of the bronchodilator effects of salbutamol delivered via a metered-dose inhaler with spacer, a dry-powder inhaler, and a jet nebulizer in patients with …

A Ikeda, K Nishimura, H Koyama, M Tsukino, T Hajiro… - Respiration, 1999 - karger.com
The aim of this study was to compare the bronchodilator effects of salbutamol delivered via
three different devices: a dry-powder inhaler (DPI), a metered-dose inhaler (MDI) with a …

An in vitro analysis of the output of salbutamol from different nebulizers

PW Barry, C O'Callaghan - European Respiratory Journal, 1999 - Eur Respiratory Soc
The objective of this study was to determine the particle size and mass output of salbutamol
from different nebulizers used under simulated breathing conditions. Seven …

Effect of a nebulizer holding chamber on aerosol delivery

RM Sarhan, AA Elberry, NS Abdelwahab… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: A new holding chamber was designed to be used with the Aerogen Solo
nebulizer to increase the aerosol emitted that reach the patient. The aim of this study was to …

In-vitro/in-vivo comparison of inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during non-invasive …

A Hassan, R Salah Eldin… - Experimental lung …, 2017 - Taylor & Francis
Background: Patients receiving noninvasive ventilation (NIV) may benefit from medical
aerosol, but most guidance on dosing with different aerosol devices is limited to in-vitro …