Diabetic kidney disease (DKD) affects approximately one-third of patients with diabetes and
taking into consideration the high cardiovascular risk burden associated to this condition a …

The renin–angiotensin–aldosterone system (RAAS) has a key role in the regulation of blood
pressure, sodium and water balance, and cardiovascular and renal homeostasis. In diabetic …

Diabetic Kidney Disease (DKD) is the leading cause of chronic kidney disease in developed
countries and its prevalence has increased dramatically in the past few decades. These …

Medications that block the renin-angiotensin-aldosterone system (RAAS) are a cornerstone
of diabetic nephropathy treatment. These agents play an important role in slowing the …

Data of numerous clinical trials show that lowering of blood pressure is prerequisite for
reducing the rate of renal function loss in chronic renal disease. There is evidence …

During the last two decades, many large-scale randomized clinical trials have confirmed the
importance of lowering blood pressure and inhibiting the renin-angiotensin-aldosterone …

Hypertension is an important independent risk factor for renal disease. If hypertension and
chronic renal disease co-exist, as is common in patients with diabetes mellitus, the risk of …

Diabetic nephropathy (diabetic kidney disease) is defined as a rise in urinary albumin
excretion rate, often associated with an increase in blood pressure, and typically with …

Chronic kidney disease (CKD), a major worldwide public-health problem which affects about
10% of the population, has an increased annual incidence rate of about 5–8%. This …

Diabetic nephropathy, the major cause of end-stage renal disease in the world occurs as a
result of both metabolic and haemodynamic insults, thus emphasizing the importance of …