Background Sub-anesthetic ketamine doses rapidly reduce depressive symptoms, although
additional investigations of the underlying neural mechanisms and the prediction of …

Background Subanesthetic ketamine infusions can elicit rapid and sustained antidepressant
effects, yet the potential cognitive impact of ketamine has not been thoroughly examined …

Methods Systematic searches were conducted at Embase, PubMed, and PsycINFO using
the terms depression, ketamine, and cognition. Title, abstract, and full-text reading were …

Background Ketamine is reported to have rapid antidepressant effects; however, there is
limited understanding of the time-course of ketamine effects beyond a single infusion. A …

Up to 20% of depressed patients demonstrate treatment resistance to one or more adequate
antidepressant trials, resulting in a disproportionately high burden of illness. Ketamine is a …

The glutamatergic modulator ketamine has been shown to rapidly reduce depressive
symptoms in patients with treatment-resistant major depressive disorder (TRD). Although its …

Objective: Subanesthetic ketamine doses have been shown to have rapid yet transient
antidepressant effects in patients with treatment-resistant depression, which may be …

Objective: Subanesthetic ketamine doses have been shown to have rapid yet transient
antidepressant effects in patients with treatment-resistant depression, which may be …

Background Ketamine demonstrated rapid antidepressant effects in treatment-resistant
depression (TRD). However, evaluation of ketamine's neurocognitive effect in TRD is …

Background Ketamine has emerged as a rapid-acting antidepressant in treatment-resistant
depression (TRD) increasingly used in non-research, clinical settings. Few studies …