Purpose Diagnosis of amyotrophic lateral sclerosis (ALS) can be difficult from clinical
symptoms alone. Diffusion tensor imaging (DTI) has been suggested as an adjunct …

Rationale and Objectives There have been a large number of case-control studies using
diffusion tensor imaging (DTI) in amyotrophic lateral sclerosis (ALS). The objective of this …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. However, no reliable
biomarkers have been identified to represent the clinical status. This study aimed to …

BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) allows direct visualization
and volumetric analysis of the corticospinal tract (CST). The purpose of this study was to …

Introduction Diffusion tensor imaging (DTI) can be used to map disease progression in
amyotrophic lateral sclerosis (ALS) and therefore is a promising candidate for a biomarker in …

Background This study was performed to assess changes in diffusion tensor imaging (DTI)
over time in patients with amyotrophic lateral sclerosis (ALS). Methods We performed DTI in …

Purpose Diffusion tensor imaging (DTI) and quantitative susceptibility mapping (QSM) have
been proposed as methods to aid in the diagnosis of amyotrophic lateral sclerosis (ALS) and …

This work evaluates the potential in diagnostic application of a new advanced neuroimaging
method, which delineates the profile of tissue properties along the corticospinal tract (CST) …

ABSTRACT Background and Purpose: Diffusion tensor imaging (DTI) was used as a
noninvasive method to evaluate the anatomy of the corticospinal tract (CST) and the pattern …

Background Amyotrophic lateral sclerosis (ALS) is characterized by pronounced clinical
heterogeneity in terms of onset and disease progression. Widespread changes in white …