Introduction: Glaucoma is the second leading cause of blindness in the world and current
pharmacotherapies for glaucoma have remained relatively unchanged (with the exception of …

Glaucoma is the most common cause of legal blindness worldwide. This progressive optic
neuropathy is characterized by the degeneration of retinal ganglion cells and consequent …

Glaucoma is a neurodegenerative disease with an estimated prevalence of 60 million
people, and the most common cause of irreversible blindness worldwide. The mainstay of …

Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …

During the last 30 years, the definition of glaucoma as been revised to eliminate the
inclusion of intraocular pressure. Open angle glaucoma is the second leading cause of …

Highlights•Medical glaucoma therapy reduces intraocular pressure.•Most available drugs do
not tackle the origin of glaucoma.•Causative glaucoma treatment is crucial to improve …

Open-angle glaucoma is a multifactorial optic neuropathy characterized by progressive loss
of retinal ganglion cells and their axons. It is an irreversible disease with no established …

Purpose: To investigate the trends and progresses in glaucoma research by searching two
major clinical trial registries; clinicaltrials. gov, and Australianclinicaltrials. gov. au. Methods …

In most retinal diseases, neuronal loss is the main cause of vision loss. Neuroprotection is
the alteration of neurons and/or their environment to encourage the survival and function of …

Glaucoma as a neurodegenerative disease is a valid working hypothesis to understand
neural injury in the visual system. This paradigm may stimulate the discovery of innovative …