C3 glomerulopathy: understanding an ultra‐rare complement‐mediated renal disease

AK Heiderscheit, JJ Hauer… - American Journal of …, 2022 - Wiley Online Library
Abstract C3 glomerulopathy (C3G) describes a pathologic pattern of injury diagnosed by
renal biopsy. It is characterized by the dominant deposition of the third component of …

Update on C3 glomerulopathy: a complement-mediated disease

F Caravaca-Fontán, L Lucientes, T Cavero, M Praga - Nephron, 2020 - karger.com
Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …

C3 glomerulopathy—understanding a rare complement-driven renal disease

RJH Smith, GB Appel, AM Blom, HT Cook… - Nature reviews …, 2019 - nature.com
The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …

Complement inhibition in C3 glomerulopathy

CM Nester, RJH Smith - Seminars in immunology, 2016 - Elsevier
Abstract C3 glomerulopathy (C3G) describes a spectrum of glomerular diseases defined by
shared renal biopsy pathology: a predominance of C3 deposition on immunofluorescence …

[HTML][HTML] C3 glomerulopathy

HT Cook - F1000Research, 2017 - ncbi.nlm.nih.gov
C3 glomerulopathy is a recently defined entity that encompasses a group of kidney diseases
caused by abnormal control of complement activation with deposition of complement …

C3 glomerulopathy: the genetic and clinical findings in dense deposit disease and C3 glomerulonephritis

X Xiao, MC Pickering, RJH Smith - Seminars in thrombosis and …, 2014 - thieme-connect.com
C3 glomerulopathy (C3G) defines a group of very rare renal diseases in which dysregulation
of the alternative and terminal complement pathways plays a pivotal pathogenic role …

C3 glomerulopathy: a new classification

F Fakhouri, V Frémeaux-Bacchi, LH Noël… - Nature Reviews …, 2010 - nature.com
Several distinct pathological patterns of glomerular inflammation are associated with
abnormal regulation of the complement system, specifically, with dysregulation of the …

Current concepts in C3 glomerulopathy

S Thomas, D Ranganathan, L Francis… - Indian journal of …, 2014 - journals.lww.com
Complement component 3 glomerulopathy (C3G) is a recently defined entity comprising of
dense deposit disease and C3 glomerulonephritis. The key histological feature is the …

[HTML][HTML] C3 glomerulopathy: a review with emphasis on ultrastructural features

J Hou, KYM Ren, M Haas - Glomerular Diseases, 2022 - karger.com
Abstract C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the
alternative complement pathway, resulting in the deposition of complement component 3 …

C3 glomerulopathy and current dilemmas

N Ito, R Ohashi, M Nagata - Clinical and experimental nephrology, 2017 - Springer
Abstract C3 glomerulopathy (C3G) is a recently identified disease entity caused by
dysregulation of the alternative complement pathway, and dense deposit disease (DDD) …