Imaging the structural connectome with hybrid diffusion MRI-microscopy tractography

S Zhu, IN Huszar, M Cottaar, G Daubney, N Eichert… - bioRxiv, 2024 - biorxiv.org
Neuroanatomical tract tracing methods are fundamental in providing" gold standard"
estimates of brain connectivity. However, tracer methods cannot be performed in humans …

Limits to anatomical accuracy of diffusion tractography using modern approaches

KG Schilling, V Nath, C Hansen, P Parvathaneni… - Neuroimage, 2019 - Elsevier
Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the
brain, with a range of applications in both clinical and basic neuroscience. Despite …

[HTML][HTML] Diffusion MRI-based cortical connectome reconstruction: dependency on tractography procedures and neuroanatomical characteristics

MRT Sinke, WM Otte, D Christiaens, O Schmitt… - Brain Structure and …, 2018 - Springer
Diffusion MRI (dMRI)-based tractography offers unique abilities to map whole-brain
structural connections in human and animal brains. However, dMRI-based tractography …

When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity

DB Aydogan, R Jacobs, S Dulawa… - Brain Structure and …, 2018 - Springer
Tractography is a powerful technique capable of non-invasively reconstructing the structural
connections in the brain using diffusion MRI images, but the validation of tractograms is …

A diffusion MRI tractography connectome of the mouse brain and comparison with neuronal tracer data

E Calabrese, A Badea, G Cofer, Y Qi… - Cerebral …, 2015 - academic.oup.com
Interest in structural brain connectivity has grown with the understanding that abnormal
neural connections may play a role in neurologic and psychiatric diseases. Small animal …

Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited

C Thomas, FQ Ye, MO Irfanoglu… - Proceedings of the …, 2014 - National Acad Sciences
Tractography based on diffusion-weighted MRI (DWI) is widely used for mapping the
structural connections of the human brain. Its accuracy is known to be limited by technical …

Diffusion MRI fiber tractography of the brain

B Jeurissen, M Descoteaux, S Mori… - NMR in …, 2019 - Wiley Online Library
The ability of fiber tractography to delineate non‐invasively the white matter fiber pathways
of the brain raises possibilities for clinical applications and offers enormous potential for …

[HTML][HTML] The role of spatial embedding in mouse brain networks constructed from diffusion tractography and tracer injections

S Trinkle, S Foxley, G Wildenberg, N Kasthuri… - Neuroimage, 2021 - Elsevier
Diffusion MRI tractography is the only noninvasive method to measure the structural
connectome in humans. However, recent validation studies have revealed limitations of …

[HTML][HTML] Using mesoscopic tract-tracing data to guide the estimation of fiber orientation distributions in the mouse brain from diffusion MRI

Z Liang, TM Arefin, CH Lee, J Zhang - Neuroimage, 2023 - Elsevier
Diffusion MRI (dMRI) tractography is the only tool for non-invasive mapping of macroscopic
structural connectivity over the entire brain. Although it has been successfully used to …

[HTML][HTML] Insights from the IronTract challenge: Optimal methods for mapping brain pathways from multi-shell diffusion MRI

C Maffei, G Girard, KG Schilling, DB Aydogan, N Adluru… - NeuroImage, 2022 - Elsevier
Limitations in the accuracy of brain pathways reconstructed by diffusion MRI (dMRI)
tractography have received considerable attention. While the technical advances …