Biochemical Marker Assessment of Chronic Carbamazepine Exposure at Environmentally Relevant Concentrations in Juvenile Common Carp (Cyprinus carpio)

X Liang, Z Csenki, B Ivánovics, I Bock, B Csorbai… - Antioxidants, 2022 - mdpi.com
Worldwide, the anticonvulsant drug carbamazepine (CBZ) is the most frequently identified
pharmaceutical residue detected in rivers. Reported chronic effects of CBZ in non-target …

Hepatic antioxidant status and hematological parameters in rainbow trout, Oncorhynchus mykiss, after chronic exposure to carbamazepine

ZH Li, J Velisek, V Zlabek, R Grabic, J Machova… - Chemico-biological …, 2010 - Elsevier
Recently, residual pharmaceuticals are generally recognized as relevant sources of aquatic
environmental pollutants. However, the toxicological effects of these contaminants have not …

Acute toxicity of carbamazepine to juvenile rainbow trout (Oncorhynchus mykiss): effects on antioxidant responses, hematological parameters and hepatic EROD

ZH Li, V Zlabek, J Velisek, R Grabic, J Machova… - Ecotoxicology and …, 2011 - Elsevier
Awareness of residual pharmaceutically active compounds (PhACs) in the aquatic
environment is growing as investigations into these pollutants are increasing and analytical …

Physiological condition status and muscle‐based biomarkers in rainbow trout (Oncorhynchus mykiss), after long‐term exposure to carbamazepine

ZH Li, V Zlabek, J Velisek, R Grabic… - Journal of Applied …, 2010 - Wiley Online Library
Recently, residual pharmaceuticals are generally recognized as relevant sources of aquatic
environmental pollutants. However, the toxicological effects of these contaminants have not …

Short-term exposure to carbamazepine causes oxidative stress on common carp (Cyprinus carpio)

E Gasca-Pérez, M Galar-Martínez… - Environmental …, 2019 - Elsevier
The aim of this research was to determine the bioconcentration factor and if subacute
exposure to carbamazepine (2 mg L− 1) modifies the oxidative state of liver, gills and brain …

Bioaccumulation and bioconcentration of carbamazepine and other pharmaceuticals in fish under field and controlled laboratory experiments. Evidences of …

ME Valdés, B Huerta, DA Wunderlin, MA Bistoni… - Science of the Total …, 2016 - Elsevier
There is a growing interest in evaluating the presence of pharmaceutical residues and their
metabolites in aquatic biota. In this study, twenty pharmaceuticals, including carbamazepine …

Effect of a human pharmaceutical carbamazepine on antioxidant responses in brain of a model teleost in vitro: an efficient approach to biomonitoring

ZH Li, P Li, T Randak - Journal of Applied Toxicology, 2010 - Wiley Online Library
Residual pharmaceuticals are generally recognized as relevant sources of aquatic
environmental pollutants. In this study, the effects of carbamazepine (CBZ) on the …

Multilevel assessment of carbamazepine effects: An integrative approach using zebrafish early-life stages

ML da Silva, TS Andrade, RAR Villacis… - Chemosphere, 2024 - Elsevier
Carbamazepine (CBZ) is the most commonly used drug in epilepsy treatment, and its
metabolites are commonly detected among persistent pharmaceuticals in the aquatic …

Toxic effects and bioaccumulation of carbamazepine evaluated by biomarkers measured in organisms of different trophic levels

G Vernouillet, P Eullaffroy, A Lajeunesse, C Blaise… - Chemosphere, 2010 - Elsevier
The antiepileptic drug carbamazapine (CBZ) readily persists in sewage-water treatment
plant wastewaters and finds its way into receiving water bodies. Our study sought to …

Modulation of antioxidant defence system in brain of rainbow trout (Oncorhynchus mykiss) after chronic carbamazepine treatment

ZH Li, V Zlabek, J Velisek, R Grabic, J Machova… - … and Physiology Part C …, 2010 - Elsevier
We investigated the effect of long-term exposure to CBZ on the antioxidant system in brain
tissue of rainbow trout. Fish were exposed to sublethal concentrations of CBZ (1.0 μg/L, 0.2 …