[图书][B] Alcohol and Diet-Induced Disruptions to Vagal Circuits Regulating Insulin Function

BN Keller - 2023 - search.proquest.com
Alcohol use disorder (AUD) and diet-induced obesity are highly prevalent and heterogenous
conditions that can lead to increased risk of development of chronic metabolic disorders …

Ethanol inhibits pancreatic projecting neurons in the dorsal motor nucleus of the vagus

BN Keller, PA Randall, AC Arnold, KN Browning… - Brain Research …, 2022 - Elsevier
Alcohol use disorder (AUD) is a rapidly growing concern in the United States. Current
trending escalations of alcohol use are associated with a concurrent rise in alcohol-related …

cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice

CB Blake, BN Smith - American Journal of Physiology …, 2014 - journals.physiology.org
Pathologies in which insulin is dysregulated, including diabetes, can disrupt central vagal
circuitry, leading to gastrointestinal and other autonomic dysfunction. Insulin affects whole …

[HTML][HTML] Involvement of the dorsal vagal complex in alcohol-related behaviors

BN Keller, A Hajnal, KN Browning… - Frontiers in Behavioral …, 2022 - frontiersin.org
The neurobiological mechanisms that regulate the development and maintenance of alcohol
use disorder (AUD) are complex and involve a wide variety of within and between systems …

Effect of insulin on excitatory synaptic transmission onto dopamine neurons of the ventral tegmental area in a mouse model of hyperinsulinemia

S Liu, G Labouebe, S Karunakaran, SM Clee… - Nutrition & …, 2013 - nature.com
Obesity has drastically increased over the last few decades. Obesity is associated with
elevated insulin levels, which can gain access to the brain, including into dopamine neurons …

Insulin reduces excitation in gastric-related neurons of the dorsal motor nucleus of the vagus

CB Blake, BN Smith - American Journal of Physiology …, 2012 - journals.physiology.org
The dorsal motor nucleus of the vagus (DMV) in the caudal brain stem is composed mainly
of preganglionic parasympathetic neurons that control the subdiaphragmatic viscera and …

Musings on the wanderer: What's new in our understanding of vago-vagal reflexes? VI. Central vagal circuits that control glucose metabolism

S Pitra, BN Smith - American Journal of Physiology …, 2021 - journals.physiology.org
Neurons in the brain stem dorsal vagal complex (DVC) take part in a continuous
bidirectional crosstalk, in which they receive and respond to a vast array of signaling …

[HTML][HTML] Nutrient Sensing, Nutrition, and Metabolism: Musings on the wanderer: What's new in our understanding of vago-vagal reflexes? VI. Central vagal circuits that …

S Pitra, BN Smith - … Journal of Physiology-Gastrointestinal and Liver …, 2021 - ncbi.nlm.nih.gov
Neurons in the brain stem dorsal vagal complex (DVC) take part in a continuous
bidirectional crosstalk, in which they receive and respond to a vast array of signaling …

Vagus nerve damage increases alcohol intake and preference in a nonpreferring rat line: Relationship to vagal regulation of the hypothalamic–pituitary–adrenal axis

BN Keller, AE Snyder, CR Coker… - Alcohol: Clinical and …, 2024 - Wiley Online Library
Background Clinical and preclinical research indicates that gastric weight loss surgeries,
such as Roux‐en‐Y gastric bypass surgery, can induce alcohol use disorder (AUD). While …

[HTML][HTML] Vagal afferent dysfunction in obesity: cause or effect

AJ Page - The Journal of physiology, 2016 - ncbi.nlm.nih.gov
The gastrointestinal (GI) tract plays a vital role in the initiation of processes that regulate food
intake and blood glucose levels. The advances in our understanding of the signalling …