The role of microcirculation in skeletal muscle is to provide the supply of oxygen and various
nutrients and to remove waste products of muscle metabolism. As skeletal muscles are …

This review strikes at the very heart of how the microcirculation functions to facilitate blood-
tissue oxygen, substrate, and metabolite fluxes in skeletal muscle. Contemporary evidence …

Blood flow in skeletal muscle serves to supply nutrients to the muscle fibers and to remove
metabolites; it controls tissue growth and atrophy, and determines the response of muscle in …

Flow through the vascular bed of an organ is mainly regulated by diameter changes in the
arterioles which are the most important resistance vessels [19]. Spontaneous, rhythmic …

It is widely acknowledged that maintenance of muscle, size, strength and endurance is
necessary for quality of life and the role that skeletal muscle microcirculation plays in muscle …

In skeletal muscle, the size of the capillary bed is adapted to the type of muscle metabolism
and can be altered by adaptation to different environments or increased activity. Muscle …

New findings• What is the topic of this review? This review presents the paradigm shift in our
understanding of capillary structure and function that has occurred since 1920 (August …

Different capillary supply to various muscles, implying a different pattern of growth, was first
described by Ranvier [23] in white and red muscles in rabbits. Romanul [24] was the first to …

The aim of this treatise is to summarize the current understanding of the mechanisms for
blood flow control to skeletal muscle under resting conditions, how perfusion is elevated …

The age-related reduction in exercise capacity is associated with a reduction in cardiac
output and maximal oxygen consumption (Vo 2max). The loss of muscle mass explains a …