It has been suggested that cerebral blood flow (CBF) alterations may be involved in the
pathogenesis of Alzheimer's disease (AD). However, how CBF changes with age has not …

Abstract β‐amyloid (Aβ) deposits in brain blood vessel walls underlie the vascular pathology
of Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA). Growing evidence has …

Vascular disorders can either be cause or consequence in the pathophysiology of
Alzheimer's disease (AD). To comprehensively characterize the occurrence of vascular …

There is accumulating evidence suggesting that changes in brain perfusion are present long
before the clinical symptoms of Alzheimer's disease (AD), perhaps even before amyloid-β …

Cardiovascular risk factors, especially hypertension, are also major risk factors for
Alzheimer's disease (AD). To elucidate the underlying vascular origin of neurodegenerative …

Vascular changes are thought to contribute to the development of Alzheimer's disease, and
both cerebral blood flow and its responses during neural activation are reduced before …

Alzheimer's disease (AD) is defined by senile plaques, tauopathy and neuronal cell death in
specific area of the brain. Recent studies suggest that neurovascular dysfunction may be an …

Alzheimer's disease (AD) is a devastating neurological degenerative disorder and is the
most common cause of dementia in the elderly. Clinically, AD manifests with memory and …

Objective: To investigate variation in the characteristics of regional cerebral blood flow
(rCBF), brain activity, and intrinsic functional connectivity (FC) across the Alzheimer's …

Background Cerebrovascular dysfunction plays a critical role in the pathogenesis of
Alzheimer's disease (AD): the most common cause of dementia in the elderly. The …