Mast cells are primary cells initiating allergic inflammation by the release of various allergic
mediators, such as histamine and pro-inflammatory cytokines. Aspalathin (ASP) is the …

Background Mast cells play important roles in allergic inflammatory responses because they
produce leukotrienes (LT s), prostaglandins (PG s), and a variety of inflammatory cytokines …

Mast cells play a crucial role in allergic diseases via the release of inflammatory mediators,
particularly histamine and pro-inflammatory cytokines. Avenanthramide (Avn) C, a …

Background Oleanolic acid (OA) is an active compound found in a variety of medicinal herbs
and plants. Though OA has been widely attributed with a variety of biological activities …

The effects of asiaticoside (AS) on allergic responses mediated by mast cells were
investigated. AS showed no obvious cytotoxicity on RPMCs (rat peritoneal mast cells). AS …

The various clinical approaches for treating allergy-related diseases have shown modest
progress in low side effects and improved clinical outcomes. Therefore, finding alternative …

More than 20% of the world's population suffers from allergic diseases, including allergic
asthma, rhinitis, and atopic dermatitis that severely reduce the patient's quality of life. The …

Mast cells play an essential role in IgE‐FcεR1‐mediated allergic diseases. Citrus aurantium
is a prolific source of flavonoids with various biological activities, including anti …

Scoparone is known to have a wide range of pharmacological properties in vitro. However,
the roles of scoparone in immediate-type allergic reactions have not yet been investigated …

Mast cells participate in allergy and inflammation by secreting inflammatory mediators such
as histamine and proinflammatory cytokines. Flavonoids are naturally occurring molecules …