Neurons in the brain stem dorsal vagal complex (DVC) take part in a continuous
bidirectional crosstalk, in which they receive and respond to a vast array of signaling …

Neurons in the brain stem dorsal vagal complex (DVC) take part in a continuous
bidirectional crosstalk, in which they receive and respond to a vast array of signaling …

Maintaining blood glucose at an appropriate physiological level requires precise
coordination of multiple organs and tissues. The vagus nerve bidirectionally connects the …

The dorsal vagal complex (DVC) is a brainstem site regulating diverse aspects of physiology
including food intake and blood glucose homeostasis. Astrocytes are purported to play an …

Highlights•Vagal afferent neurons (VANs) directly sense fats, carbohydrates and possibly
proteins.•Update on GLP1 and ghrelin signaling in VANs.•Novel role of VANs in the long …

Brain senses nutrients and initiates negative feedback responses to regulate whole-body
nutrient metabolism. Detection of changes in circulating nutrients is achieved at sites such …

Neurons in the brainstem dorsal vagal complex integrate neural and humoral signals to
coordinate autonomic output to viscera that regulate a variety of physiological functions, but …

The gastrointestinal tract has its own “brain,” the enteric nervous system or ENS, that
executes routine housekeeping functions of digestion. The dorsal vagal complex in the …

Glucose sensing within autonomic neurocircuits is critical for the effective integration and
regulation of a variety of physiological homeostatic functions including the co-ordination of …

The gastrointestinal (GI) tract plays a vital role in the initiation of processes that regulate food
intake and blood glucose levels. The advances in our understanding of the signalling …