Irritable bowel syndrome (IBS) is a chronic, recurring, and remitting functional disorder of the
gastrointestinal tract characterized by abdominal pain, distention, and changes in bowel …

Irritable bowel syndrome (IBS) is a clinically well-defined chronic condition that is now
understood as a disorder of gut-brain regulation, as established in the work of the Rome IV …

Substance P (SP) is an important neurotransmitter that mediates various gut functions;
however, its precise pathophysiological role remains unclear. In this study, we investigated …

Abstract Background/Aims: Tachykinins participate in somatic pain and intestinal motility
control. The role of tachykinin receptors in both colonic motor disturbances and visceral pain …

Background: Irritable bowel syndrome (IBS) is a chronic, recurrent bowel disorder with an
unknown etiology, which is most likely multifactorial. Increased mucosal permeability …

In the gastrointestinal tract, tachykinins are peptide neurotransmitters in nerve circuits that
regulate intestinal motility, secretion, and vascular functions. Tachykinins also contribute to …

Background and Purpose Irritable bowel syndrome (IBS) is defined as an association of
chronic abdominal pain with bowel habit abnormalities, without clear organic dysfunction. T …

Vol. 30, No. 1 January, 2024 (4-6) 5 tamine receptor 4 agonist similar to tegaserod, is not
included in the AGA IBS-C guidelines due to a lack of studies evaluating its efficacy in IBS-C …

Introduction: Irritable bowel syndrome (IBS) is a prevalent gastrointestinal (GI) disease.
Antispasmodics are a heterogeneous group of drugs that tackle IBS-associated altered …

Irritable bowel syndrome (IBS) is a functional gastrointestinal disease characterized by
visceral hypersensitivity‐related abdominal pain, in which diarrhea‐predominant IBS (IBS …