[HTML][HTML] OMICS in chronic kidney disease: focus on prognosis and prediction

M Provenzano, R Serra, C Garofalo, A Michael… - International Journal of …, 2021 - mdpi.com
Chronic kidney disease (CKD) patients are characterized by a high residual risk for
cardiovascular (CV) events and CKD progression. This has prompted the implementation of …

[HTML][HTML] The use of 'omics for diagnosing and predicting progression of chronic kidney disease: a scoping review

MA Govender, JT Brandenburg, J Fabian… - Frontiers in …, 2021 - frontiersin.org
Globally, chronic kidney disease (CKD) contributes substantial morbidity and mortality.
Recently, various 'omics platforms have provided insight into the molecular basis of kidney …

[HTML][HTML] Applying proteomics and integrative “Omics” strategies to decipher the chronic kidney disease-related atherosclerosis

J Tracz, M Luczak - International Journal of Molecular Sciences, 2021 - mdpi.com
Patients with chronic kidney disease (CKD) are at increased risk of atherosclerosis and
premature mortality, mainly due to cardiovascular events. However, well-known risk factors …

[HTML][HTML] Contribution of predictive and prognostic biomarkers to clinical research on chronic kidney disease

M Provenzano, S Rotundo, P Chiodini… - International Journal of …, 2020 - mdpi.com
Chronic kidney disease (CKD), defined as the presence of albuminuria and/or reduction in
estimated glomerular filtration rate (eGFR)< 60 mL/min/1.73 m2, is considered a growing …

The application of multi-omics and systems biology to identify therapeutic targets in chronic kidney disease

K Cisek, M Krochmal, J Klein… - Nephrology Dialysis …, 2016 - academic.oup.com
The quest for the ideal therapeutic target in chronic kidney disease (CKD) has been riddled
with many obstacles stemming from the molecular complexity of the disease and its co …

Integrated multi-omics approaches to improve classification of chronic kidney disease

S Eddy, LH Mariani, M Kretzler - Nature Reviews Nephrology, 2020 - nature.com
Chronic kidney diseases (CKDs) are currently classified according to their clinical features,
associated comorbidities and pattern of injury on biopsy. Even within a given classification …

[HTML][HTML] Chronic Kidney Disease: Early Detection, Mechanisms, and Therapeutic Implications

C Delrue, MM Speeckaert - Journal of Personalized Medicine, 2023 - mdpi.com
Chronic Kidney Disease (CKD) constitutes a global health crisis, silently affecting millions
worldwide. This condition, characterized by a gradual decline in kidney function, places a …

[HTML][HTML] New potential biomarkers for chronic kidney disease management—A review of the literature

I Lousa, F Reis, I Beirão, R Alves, L Belo… - International Journal of …, 2020 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and the mortality
rate continues to be unacceptably high. The biomarkers currently used in clinical practice …

[HTML][HTML] Novel biomarkers in the diagnosis of chronic kidney disease and the prediction of its outcome

J Rysz, A Gluba-Brzózka, B Franczyk… - International journal of …, 2017 - mdpi.com
In its early stages, symptoms of chronic kidney disease (CKD) are usually not apparent.
Significant reduction of the kidney function is the first obvious sign of disease. If diagnosed …

[HTML][HTML] Chronic Kidney Disease: Underlying Molecular Mechanisms—A Special Issue Overview

L Belo, M Carvalho - International Journal of Molecular Sciences, 2023 - mdpi.com
Chronic kidney disease (CKD) is an epidemic health issue that requires global attention [1].
The worldwide increment of CKD incidence is related to an increase in traditional risk factors …