[HTML][HTML] Comprehensive atlas of the myelin basic protein interaction landscape

EV Smirnova, TV Rakitina, RH Ziganshin, GP Arapidi… - Biomolecules, 2021 - mdpi.com
Intrinsically disordered myelin basic protein (MBP) is one of the key autoantigens in
autoimmune neurodegeneration and multiple sclerosis particularly. MBP is highly positively …

[HTML][HTML] Identification of Myelin Basic Protein Proximity Interactome Using TurboID Labeling Proteomics

EV Smirnova, TV Rakitina, RH Ziganshin, GA Saratov… - Cells, 2023 - mdpi.com
Myelin basic protein (MBP) is one of the key structural elements of the myelin sheath and
has autoantigenic properties in multiple sclerosis (MS). Its intracellular interaction network is …

Identification of Novel Site‐Specific Alterations in the Modification Level of Myelin Basic Protein Isolated from Mouse Brain at Different Ages Using Capillary …

B Sarg, K Faserl, HH Lindner - Proteomics, 2017 - Wiley Online Library
Myelin basic protein (MBP) is a multifunctional protein involved in maintaining the stability
and integrity of the myelin sheath by a variety of interactions with membranes and other …

[HTML][HTML] Multiple sclerosis: an important role for post-translational modifications of myelin basic protein in pathogenesis

JK Kim, FG Mastronardi, DD Wood, DM Lubman… - Molecular & Cellular …, 2003 - ASBMB
Myelin basic protein (MBP) represents a candidate autoantigen in multiple sclerosis (MS).
We isolated MBP from normal and MS human white matter and purified six components …

Thermodynamic analysis of the disorder-to-α-helical transition of 18.5-kDa myelin basic protein reveals an equilibrium intermediate representing the most compact …

KA Vassall, AD Jenkins, VV Bamm, G Harauz - Journal of molecular biology, 2015 - Elsevier
Abstract The intrinsically disordered, 18.5-kDa isoform of myelin basic protein (MBP) is a
peripheral membrane protein that is essential to proper myelin formation in the central …

[HTML][HTML] BMP7 retards peripheral myelination by activating p38 MAPK in Schwann cells

X Liu, Y Zhao, S Peng, S Zhang, M Wang, Y Chen… - Scientific Reports, 2016 - nature.com
Schwann cell (SC) myelination is pivotal for the proper physiological functioning of the
nervous system, but the underlying molecular mechanism remains less well understood …

Continuous elution proteoform identification of myelin basic protein by superficially porous reversed-phase liquid chromatography and Fourier transform mass …

DA Plymire, CE Wing, DE Robinson… - Analytical …, 2017 - ACS Publications
Myelin basic protein (MBP) plays an important structural and functional role in the neuronal
myelin sheath. Translated MBP exhibits extreme microheterogeneity with numerous …

Molecular evolution of myelin basic protein, an abundant structural myelin component

S Nawaz, J Schweitzer, O Jahn, HB Werner - Glia, 2013 - Wiley Online Library
Rapid nerve conduction in jawed vertebrates is facilitated by the myelination of axons, which
evolved in ancient cartilaginous fish. We aim to understand the coevolution of myelin and …

[HTML][HTML] Deconvolution of the MBP-Bri2 Interaction by a Yeast Two Hybrid System and Synergy of the AlphaFold2 and High Ambiguity Driven Protein-Protein Docking

EV Smirnova, TV Rakitina, GA Saratov, AA Kudriaeva… - Crystals, 2022 - mdpi.com
Myelin basic protein (MBP) is one of the key proteins in the development of multiple
sclerosis (MS). However, very few intracellular MBP partners have been identified up to now …

The classic basic protein of myelin-conserved structural motifs and the dynamic molecular barcode involved in membrane adhesion and protein-protein interactions

G Harauz, DS Libich - Current Protein and Peptide Science, 2009 - ingentaconnect.com
The myelin basic protein (MBP) family comprises a variety of developmentally-regulated
members arising from different transcription start sites, differential splicing, and post …