BACKGROUND: In previous trials, UV therapy has been demonstrated to be effective in the
treatment of localized scleroderma (LS). To date, a randomized comparison study to …

BACKGROUND: Recent studies suggest that ultraviolet (UV) A1 phototherapy is an effective
treatment for localized scleroderma (LS); however, the optimum UVA1 dose remains to be …

Background: For treatment of localized scleroderma numerous treatments, including ones
with potentially hazardous side effects, are currently used with only limited success …

Summary Background Ultraviolet (UV) A1 phototherapy is an effective anti‐inflammatory
treatment modality that influences fibroblast functions. Objectives To document the effects of …

BACKGROUND: Ultraviolet (UV) A-1 phototherapy is now available for a variety of skin
diseases. Increasingly since 1995, there have been investigations of the efficacy of UVA-1 …

Purpose: To evaluate the efficacy of medium-dose UVA1 phototherapy in patients with
localized scleroderma. Method: A controlled pilot study with medium-dose UVA1 (48 J/cm2) …

Background: The presence of an inflammatory infiltrate consisting of helper T cells and a
dysregulated matrix metabolism leading to excessive deposition of collagen are two …

Until recently, various therapies for localized scleroderma have been used with limited
success. Recently, phototherapy, with or without psoralen, was proposed as a successful …

Background: Lichen sclerosus (LS) is a chronic inflammatory skin disease in which
numerous therapies have been used, with only limited success. Because low-dose UVA1 …

Background: The efforts to treat localized scleroderma, including therapies with potentially
hazardous side effects, are often unsatisfactory. Recently, PUVA-bath photochemotherapy …