SSc is a chronic progressive disorder of unknown aetiology characterized by excess
synthesis and deposition of collagen and other extracellular matrix components in a variety …

BACKGROUND: Systemic sclerosis is a multisystemic connective tissue disease with
marked involvement of the skin and joints for which few effective evidence based therapies …

Localized scleroderma is a rare autoimmune disease with primary affection of the skin, and
occasional involvement of the fat tissue, muscle, fascia, and bone. Depending on the clinical …

Whole‐body ultraviolet (UV) A1 (340–400 nm) phototherapy was first introduced 30 years
ago, but is currently available in the UK in only three dermatology departments. A workshop …

To the Editor: Although graft-versus-host disease (GVHD) affecting internal organs can be
treated successfully with immunosuppressive drugs and extracorporeal photopheresis …

PUVA therapy was carried out on four patients with scleroderma; three of them had
cutaneous manifestations of progressive systemic sclerosis and one other exhibited …

We established diagnostic criteria and severity classification of localized scleroderma
because there is no established diagnostic criteria or widely accepted severity classification …

BACKGROUND: Psoralen-UVA (PUVA) and narrowband UVB (311-nm) therapy are
considered to be first-line phototherapies for patients with moderate to severe psoriasis. To …

Summary Background Localized scleroderma (LoS) is characterized by a phase of disease
activity followed by remission. However, disease recurrences occur. Knowledge concerning …

Background In previous studies, distinct immunological abnormalities have been reported in
localized scleroderma (LS). Several pro‐inflammatory cytokines have been demonstrated at …