Comprehensive evaluation of electrophysiological and 3D structural features of human atrial myocardium with insights on atrial fibrillation maintenance mechanisms
Atrial fibrillation (AF) occurrence and maintenance is associated with progressive
remodeling of electrophysiological (repolarization and conduction) and 3D structural …
remodeling of electrophysiological (repolarization and conduction) and 3D structural …
Three‐dimensional integrated functional, structural, and computational mapping to define the structural “fingerprints” of heart‐specific atrial fibrillation drivers in human …
Background Structural remodeling of human atria plays a key role in sustaining atrial
fibrillation (AF), but insufficient quantitative analysis of human atrial structure impedes the …
fibrillation (AF), but insufficient quantitative analysis of human atrial structure impedes the …
[HTML][HTML] Structural and functional remodeling of the left atrium: clinical and therapeutic implications for atrial fibrillation
Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice.
Despite advances in our understanding of the pathophysiology of this complex arrhythmia …
Despite advances in our understanding of the pathophysiology of this complex arrhythmia …
Atrial fibrillation driver mechanisms: insight from the isolated human heart
Although there have been great technological advances in the treatment of atrial fibrillation
(AF), current therapies remain limited due to a narrow understanding of AF mechanisms in …
(AF), current therapies remain limited due to a narrow understanding of AF mechanisms in …
Electrophysiological characteristics of permanent atrial fibrillation: insights from research models of cardiac remodeling
Atrial fibrillation (AF) results in a remodeling of the electrical and structural characteristics of
the cardiac tissue which dramatically reduces the efficacy of pharmacological and catheter …
the cardiac tissue which dramatically reduces the efficacy of pharmacological and catheter …
Fibrosis and atrial fibrillation: computerized and optical mapping: a view into the human atria at submillimeter resolution
Recent studies strongly suggest that the majority of atrial fibrillation (AF) patients with
diagnosed or subclinical cardiac diseases have established or even pre-existing fibrotic …
diagnosed or subclinical cardiac diseases have established or even pre-existing fibrotic …
Structural remodeling in atrial fibrillation
D Corradi, S Callegari, R Maestri, S Benussi… - Nature clinical practice …, 2008 - nature.com
Atrial fibrillation occurs and maintains itself in the context of a morphologically and
functionally altered atrial substrate that can be induced by stressors such as underlying …
functionally altered atrial substrate that can be induced by stressors such as underlying …
Improved understanding of the pathophysiology of atrial fibrillation through the lens of discrete pathological pathways
MA Balouch, MJ Kolek, D Darbar - Global Cardiology Science and …, 2014 - qscience.com
Atrial fibrillation (AF) is a common disorder with a complex and incompletely understood
pathophysiology. Genetic approaches to understanding the pathophysiology of AF have led …
pathophysiology. Genetic approaches to understanding the pathophysiology of AF have led …
Molecular insights in atrial fibrillation pathogenesis and therapeutics: a narrative review
KA Papathanasiou, SG Giotaki, DA Vrachatis, G Siasos… - Diagnostics, 2021 - mdpi.com
The prevalence of atrial fibrillation (AF) is bound to increase globally in the following years,
affecting the quality of life of millions of people, increasing mortality and morbidity, and …
affecting the quality of life of millions of people, increasing mortality and morbidity, and …
Atrial heterogeneity generates re-entrant substrate during atrial fibrillation and anti-arrhythmic drug action: mechanistic insights from canine atrial models
Anti-arrhythmic drug therapy is a frontline treatment for atrial fibrillation (AF), but its success
rates are highly variable. This is due to incomplete understanding of the mechanisms of …
rates are highly variable. This is due to incomplete understanding of the mechanisms of …