This study aimed to test for the possible antinociceptive effect of the naturally occurring
terpene citral in rodent models of acute and chronic orofacial pain and to test for the possible …

Background Citronellyl acetate (CAT), a monoterpene product of the secondary metabolism
of plants, has been shown in the literature to possess several different biological activities …

The aim of this research was to assess the antinociceptive activity of the transient receptor
potential (TRP) channel TRPV1, TRPM8, and TRPA1 antagonists in neurogenic, tonic, and …

Background Transient receptor potential (TRP) cation channels are involved in the
perception of hot and cold pain and are targets for pain relief in humans. We hypothesized …

Serotonin (5HT) enhances transient receptor potential V1 channel (TRPV1)–evoked
calcitonin gene-related peptide (CGRP) release from female, but not male, human dental …

Orofacial pain is a highly prevalent clinical condition, yet difficult to control effectively with
available drugs. Much attention is currently focused on the anti-inflammatory and …

Aims: To test for the possible antinociceptive effect of nifedipine in rodent models of acute
and chronic neuropathic orofacial pain and the possible involvement of TRP-and NMDA …

The transient receptor potential vanilloid 1 (TRPV1) ion channel is a member of the family of
Transient Receptor Potential (TRP) channels that acts as a molecular detector of noxious …

Aims: To evaluate the antinociceptive effects of citronellal (CTL) on formalin-, capsaicin-, and
glutamate-induced orofacial nociception in mice and to investigate whether such effects …

We tested whether it is possible to selectively block pain signals in the orofacial area by
delivering the permanently charged lidocaine derivative QX-314 into nociceptors via TPRV1 …