The roles of TRPV1, TRPA1 and TRPM8 channels in chemical and thermal sensitivity of the mouse oral mucosa
TI Kichko, W Neuhuber, G Kobal… - European Journal of …, 2018 - Wiley Online Library
Spices in food and beverages and compounds in tobacco smoke interact with sensory
irritant receptors of the transient receptor potential (TRP) cation channel family. TRPV 1 …
irritant receptors of the transient receptor potential (TRP) cation channel family. TRPV 1 …
Involvement of transient receptor potential A1 channel in algesic and analgesic actions of the organic compound limonene
T Kaimoto, Y Hatakeyama, K Takahashi… - … Journal of Pain, 2016 - Wiley Online Library
Background TRPA 1 is a Ca‐permeable nonselective cation channel expressed in sensory
neurons and acts as a nocisensor. Recent reports show that some monoterpenes, a group of …
neurons and acts as a nocisensor. Recent reports show that some monoterpenes, a group of …
[HTML][HTML] High-concentration L-menthol exhibits counter-irritancy to neurogenic inflammation, thermal and mechanical hyperalgesia caused by trans-cinnamaldehyde
The transient receptor potential cation channel subfamily M 8 (TRPM8) agonist L-menthol
has been used traditionally for its topical counterirritant properties. Although the use of …
has been used traditionally for its topical counterirritant properties. Although the use of …
Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels
Transient receptor potential ion channels (TRPs) expressed in the periphery sense and
electrically transduce noxious stimuli to transmit the signals to the brain. Many natural and …
electrically transduce noxious stimuli to transmit the signals to the brain. Many natural and …
Identification of a partial and selective TRPV1 agonist CPIPC for alleviation of inflammatory pain
L Dong, Q Zhou, Q Liang, Z Qiao, Y Liu, L Shao… - Molecules, 2022 - mdpi.com
Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel,
predominantly expressed in a subset of peripheral sensory neurons for pain signaling …
predominantly expressed in a subset of peripheral sensory neurons for pain signaling …
Acute and neuropathic orofacial antinociceptive effect of eucalyptol
JMA Melo Júnior, MBMV Damasceno… - …, 2017 - Springer
Terpenes have a wide range of pharmacological properties, including antinociceptive
action. The anti-inflammatory and antinociceptive effects of eucalyptol are well established …
action. The anti-inflammatory and antinociceptive effects of eucalyptol are well established …
Orofacial anti-hypernociceptive effect of citral in acute and persistent inflammatory models in rats
Orofacial pain has significant psychological and physiological effects. Citral (3, 7-dimethyl-2,
6-octadienal) is the main component of Cymbopogon citratus (DC) Stapf, an herb with …
6-octadienal) is the main component of Cymbopogon citratus (DC) Stapf, an herb with …
Niflumic acid, a TRPV1 channel modulator, ameliorates stavudine-induced neuropathic pain
TRP channels have been discovered as a specialized group of somatosensory neurons
involved in the detection of noxious stimuli. Desensitization of TRPV1 located on dorsal root …
involved in the detection of noxious stimuli. Desensitization of TRPV1 located on dorsal root …
Effects of an intrathecal TRPV1 antagonist, SB366791, on morphine-induced itch, body temperature, and antinociception in mice
S Sakakibara, N Imamachi, M Sakakihara… - Journal of Pain …, 2019 - Taylor & Francis
Purpose Transient receptor potential vanilloid 1 (TRPV1) not only is activated by multiple
stimuli but also is involved with histamine-induced itch. The effects of TRPV1 on morphine …
stimuli but also is involved with histamine-induced itch. The effects of TRPV1 on morphine …
Pronociceptive response elicited by TRPA1 receptor activation in mice
Ankyrin-repeat transient receptor potential 1 (TRPA1) is a member of the transient receptor
potential (TRP) channel family and it is found in sensory neurons. In the present study, we …
potential (TRP) channel family and it is found in sensory neurons. In the present study, we …