Autoimmune diseases are disorders of immune regulation where the mechanisms
responsible for self-tolerance break down and pathologic T cells overcome the protective …

The goal of immunotherapy against autoimmunity is to block pathogenic inflammation
without impairing immunity against infections and tumours. Regulatory T-cells (Tregs) play a …

Autoimmune diseases are caused by antigenically complex immune responses of the
adaptive and innate immune system against specific cells, tissues or organs. Antigen …

Artificial antigen-presenting cells (aAPCs) are synthetic versions of naturally occurring
antigen-presenting cells (APCs) that, similar to natural APCs, promote efficient T effector cell …

Current therapeutics for autoimmune conditions are usually nonspecific and induce general
immune suppression. Now, reporting in Nature, Clemente-Cesares and colleagues show …

T‐cell immunotherapy offers outstanding advantages in the treatment of various diseases,
and with the selection of appropriate targets, efficient disease treatment can be achieved. T …

Autoimmune diseases affect many people worldwide. Current treatment modalities focus on
the reduction of disease symptoms using anti-inflammatory drugs which can lead to side …

Autoimmune disease is a chronic inflammatory disease caused by disorders of immune
regulation. Antigen-specific immunotherapy has the potential to inhibit the autoreactivity of …

Autoimmunity is the assault of immune response towards self-antigens, resulting to
inflammation and tissue injury. It is staged into three phases and caused by malfunction of …

Objective To develop a nanoparticle (NP) platform that can expand both CD 4+ and CD 8+
Treg cells in vivo for the suppression of autoimmune responses in systemic lupus …