[HTML][HTML] Multiple parallel hits hypothesis in nonalcoholic fatty liver disease: revisited after a decade

H Tilg, TE Adolph, AR Moschen - Hepatology, 2021 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is an epidemic liver disease, affecting
approximately one quarter of the entire population in the world.(1) This disease …

[PDF][PDF] Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

H Tilg, AR Moschen - Hepatology, 2010 - Wiley Online Library
Whereas in most cases a fatty liver remains free of inflammation, 10%‐20% of patients who
have fatty liver develop inflammation and fibrosis (nonalcoholic steatohepatitis [NASH]) …

The pathogenesis of nonalcoholic fatty liver disease: interplay between diet, gut microbiota, and genetic background

J Yu, S Marsh, J Hu, W Feng… - … research and practice, 2016 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
world, and it comprises a spectrum of hepatic abnormalities from simple hepatic steatosis to …

[HTML][HTML] Non-alcoholic fatty liver disease and extra-hepatic cancers

C Sanna, C Rosso, M Marietti, E Bugianesi - International journal of …, 2016 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease but the
second cause of death among NAFLD patients are attributed to malignancies at both …

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

E Buzzetti, M Pinzani, EA Tsochatzis - Metabolism, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

[HTML][HTML] New insights into the pathogenesis of non-alcoholic fatty liver disease: gut-derived lipopolysaccharides and oxidative stress

D Ferro, F Baratta, D Pastori, N Cocomello, A Colantoni… - Nutrients, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. The intricate NAFLD pathogenesis is summarized by the multiple-hits …

[HTML][HTML] Nonalcoholic fatty liver disease-A multisystem disease?

I Mikolasevic, S Milic, TT Wensveen, I Grgic… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is one of the most common comorbidities
associated with overweight and metabolic syndrome (MetS). Importantly, NAFLD is one of its …

The hierarchical model of NAFLD: prognostic significance of histologic features in NASH

R Loomba, N Chalasani - Gastroenterology, 2015 - gastrojournal.org
Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver
disease in the United States. 1–3 It has been broadly subdivided into 2 categories including …

[HTML][HTML] Oxidative stress in non-alcoholic fatty liver disease. An updated mini review

AP Delli Bovi, F Marciano, C Mandato, MA Siano… - Frontiers in …, 2021 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple
factors, which may partly explain why it remains still orphan of an adequate therapeutic …

The gut‐liver axis in nonalcoholic fatty liver disease: Another pathway to insulin resistance?

E Vanni, E Bugianesi - Hepatology, 2009 - journals.lww.com
(MS), is a complex trait resulting from the interaction between multiple genes and social,
behavioral, and environmental factors. Steatosis, the histological hallmark of NAFLD, is …