Evidence-based practice use of quick-release bromocriptine across the natural history of type 2 diabetes mellitus

SS Schwartz, F Zangeneh - Postgraduate medicine, 2016 - Taylor & Francis
Objectives: To provide an evidence-based practice overview on the clinical use of
bromocriptine-quick release (QR) across the natural history of type 2 diabetes mellitus …

Randomized clinical trial of quick-release bromocriptine among patients with type 2 diabetes on overall safety and cardiovascular outcomes

JM Gaziano, AH Cincotta, CM O'Connor… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Quick-release bromocriptine (bromocriptine-QR), a D2 dopamine receptor
agonist, is indicated as a treatment for type 2 diabetes. The Cycloset Safety Trial, a 52-week …

Bromocriptine–unique formulation of a dopamine agonist for the treatment of type 2 diabetes

R Scranton, A Cincotta - Expert opinion on pharmacotherapy, 2010 - Taylor & Francis
Importance to the field: There is a large unmet need for new therapies to treat type 2
diabetes (T2DM) which reduce fasting and postprandial glucose without increasing insulin …

Quick-release bromocriptine for treatment of type 2 diabetes

N Mikhail - Current drug delivery, 2011 - ingentaconnect.com
Quick-release bromocriptine (bromocriptine-QR)(Cycloset) was approved in 2009 for the
treatment of type 2 diabetes. The exact anti-diabetic mechanism of action of bromocriptine …

Bromocriptine approved as the first medication to target dopamine activity to improve glycemic control in patients with type 2 diabetes

MA Via, H Chandra, T Araki, MV Potenza… - … syndrome and obesity …, 2010 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) continues to rise in prevalence in the United States and
worldwide. Despite advances in medical treatments for T2DM, many patients remain …

Late phase completed clinical trials investigating bromocriptine mesylate quick release as treatment of type 2 diabetes mellitus

M Siamashvili, S Davis - Expert Opinion on Pharmacotherapy, 2021 - Taylor & Francis
Introduction Bromocriptine mesylate quick release (QR) is a dopamine D2 receptor agonist
and is the only oral, primarily centrally acting drug that can be used for the treatment of …

The role of bromocriptine-QR in the management of type 2 diabetes expert panel recommendations

AJ Garber, L Blonde, ZT Bloomgarden, Y Handelsman… - Endocrine Practice, 2013 - Elsevier
Objective To review available data on the efficacy and safety of bromocriptine-QR (BQR)
and to consider its role in the management of Type 2 diabetes mellitus (T2DM). Methods …

Bromocriptine-QR therapy for the management of type 2 diabetes mellitus: developmental basis and therapeutic profile summary

P Raskin, AH Cincotta - Expert review of endocrinology & …, 2016 - Taylor & Francis
An extended series of studies indicate that endogenous phase shifts in circadian neuronal
input signaling to the biological clock system centered within the hypothalamic …

Effect of bromocriptine‐QR (a quick‐release formulation of bromocriptine mesylate) on major adverse cardiovascular events in type 2 diabetes subjects

JM Gaziano, AH Cincotta, A Vinik… - Journal of the …, 2012 - Am Heart Assoc
Background Bromocriptine‐QR (a quick‐release formulation of bromocriptine mesylate), a
dopamine D2 receptor agonist, is a US F ood and D rug A dministrration–approved …

Bromocriptine mesylate for glycemic management in type 2 diabetes mellitus

JL Kerr, EM Timpe… - Annals of …, 2010 - journals.sagepub.com
Objective: To review the pharmacologic characteristics, safety, and efficacy of bromocriptine
mesylate for glycemic control in patients with type 2 diabetes mellitus. Data Sources: A …