Integrin α6 targeted positron emission tomography imaging of hepatocellular carcinoma in mouse models

GK Feng, JC Ye, WG Zhang, Y Mei, C Zhou… - Journal of controlled …, 2019 - Elsevier
Integrin α6 emerges to be a diagnostic biomarker for hepatocellular carcinoma (HCC). Here,
we translated our previously identified integrin α6 targeted peptide RWY into a positron …

An optimized Integrin α6-targeted magnetic resonance probe for molecular imaging of hepatocellular carcinoma in mice

BQ Lin, WB Zhang, J Zhao, XH Zhou, YJ Li… - Journal of …, 2021 - Taylor & Francis
Introduction Integrin α6 is an attractive diagnostic biomarker for molecular imaging of
hepatocellular carcinoma (HCC) as it has an extremely high positive rate (approximately …

Integrin α6-targeted magnetic resonance imaging of hepatocellular carcinoma in mice

Y Zhang, J Zhao, J Cai, JC Ye, YT Xiao, Y Mei… - Molecular Imaging and …, 2020 - Springer
Purpose Magnetic resonance imaging (MRI) has a high spatial resolution for detecting
hepatocellular carcinoma (HCC). Integrin α6 has emerged as a diagnostic and prognostic …

Integrin α6-targeted positron emission tomography imaging of colorectal cancer

YT Xiao, C Zhou, JC Ye, XC Yang, ZJ Li, XB Zheng… - ACS …, 2019 - ACS Publications
Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of
cancer deaths worldwide. Integrin α6 is overexpressed in all stages of CRC which makes it a …

[HTML][HTML] Preclinical evaluation of 68Ga-radiolabeled trimeric affibody for PDGFRβ-targeting PET imaging of hepatocellular carcinoma

H Cai, Z Li, Q Shi, H Yang, L Xiao, M Li, H Lin… - European Journal of …, 2023 - Springer
Purpose Hepatocellular carcinoma (HCC) is a highly vascularized solid carcinoma and
tumor vessel–targeted molecular imaging might be effective for early diagnosis of HCC …

18F-Fluorobenzoate–labeled cystine knot peptides for PET imaging of integrin αvβ6

BJ Hackel, RH Kimura, Z Miao, H Liu… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Integrin αvβ6 is a cell surface receptor minimally expressed by healthy tissue but elevated in
lung, colon, skin, ovarian, cervical, and pancreatic cancers. A molecular PET agent for …

Clinical translation of a 68Ga-labeled integrin αvβ6–targeting cyclic radiotracer for PET imaging of pancreatic cancer

X Feng, Y Wang, D Lu, X Xu, X Zhou… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The overexpression of integrin αvβ6 in pancreatic cancer makes it a promising target for
noninvasive PET imaging. However, currently, most integrin αvβ6–targeting radiotracers are …

[HTML][HTML] An optimized integrin α6‐targeted peptide for positron emission tomography/magnetic resonance imaging of pancreatic cancer and its precancerous lesion

Y Mei, YH Li, XC Yang, C Zhou, ZJ Li… - Clinical and …, 2020 - ncbi.nlm.nih.gov
Dear Editor, Recently, we successfully developed a radiolabeled probe targeting integrin α6
for the positron emission tomography (PET)/magnetic resonance (MR) imaging of pancreatic …

PET imaging of hepatocellular carcinoma by targeting tumor-associated endothelium using [68Ga]Ga-PSMA-617

Q Lu, Y Long, K Fan, Z Shen, Y Gai, Q Liu… - European journal of …, 2022 - Springer
Objective Hepatocellular carcinoma (HCC) is a malignant tumor associated with high
morbidity and mortality rates. In many non-prostate solid tumors such as HCC, prostate …

Imaging Hepatocellular Carcinoma With 68Ga-Citrate PET: First Clinical Experience

C Mari Aparici, SC Behr, Y Seo, RK Kelley… - Molecular …, 2017 - journals.sagepub.com
While cross-sectional imaging with computed tomography (CT) and magnetic resonance
imaging is the primary method for diagnosing hepatocellular carcinoma (HCC), they provide …