[HTML][HTML] The extracellular matrix enriched with exosomes for the treatment on pulmonary fibrosis in mice
Y Yu, X Liu, Z Zhao, Z Xu, Y Qiao, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment
changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process …
changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process …
[HTML][HTML] Inhibiting collagen I production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles
Y Yan, C Du, X Duan, X Yao, J Wan, Z Jiang… - … pharmaceutica Sinica B, 2022 - Elsevier
The lung is one of the most common sites for cancer metastasis. Collagens in the lung
provide a permissive microenvironment that supports the colonization and outgrowth of …
provide a permissive microenvironment that supports the colonization and outgrowth of …
microRNA-130b-3p delivery by mesenchymal stem cells-derived exosomes confers protection on acute lung injury
X Wang, J Feng, H Dai, J Mo, B Luo, C Luo… - …, 2022 - Taylor & Francis
Objective Researchers have investigated miR-130b-3p in lung disease pathology, such as
lung fibrosis. The present study was performed to elucidate the miR-130b-3p-involved …
lung fibrosis. The present study was performed to elucidate the miR-130b-3p-involved …
[HTML][HTML] Mechanism of miR-204-5p in exosomes derived from bronchoalveolar lavage fluid on the progression of pulmonary fibrosis via AP1S2
L Zhu, Y Chen, M Chen, W Wang - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background Exosomes are nanoscale vesicles secreted by various types of cells that are
responsible for intracellular communication. Despite that bronchoalveolar lavage fluid …
responsible for intracellular communication. Despite that bronchoalveolar lavage fluid …
[HTML][HTML] Pulmonary fibroblast-specific delivery of siRNA exploiting exosomes-based nanoscaffolds for IPF treatment
H Lu, X Liu, M Zhang, H Bera, W Xu, H Jiang… - Asian Journal of …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease that leads to
interstitial inflammation, lung damage, and eventually life-threatening complications. Among …
interstitial inflammation, lung damage, and eventually life-threatening complications. Among …
[HTML][HTML] microRNA-186 in extracellular vesicles from bone marrow mesenchymal stem cells alleviates idiopathic pulmonary fibrosis via interaction with SOX4 and …
J Zhou, Y Lin, X Kang, Z Liu, W Zhang, F Xu - Stem cell research & therapy, 2021 - Springer
Background Previous reports have identified that human bone marrow mesenchymal stem
cell-derived extracellular vesicles (BMSC-EVs) with their cargo microRNAs (miRNAs) are a …
cell-derived extracellular vesicles (BMSC-EVs) with their cargo microRNAs (miRNAs) are a …
[HTML][HTML] microRNA-328 in exosomes derived from M2 macrophages exerts a promotive effect on the progression of pulmonary fibrosis via FAM13A in a rat model
MY Yao, WH Zhang, WT Ma, QH Liu, LH Xing… - … & molecular medicine, 2019 - nature.com
Currently, exosome-enclosed microRNAs (miRs) in exhaled breath have potential for
biomarker discovery in patients with pulmonary diseases. This study was performed to …
biomarker discovery in patients with pulmonary diseases. This study was performed to …
[HTML][HTML] Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2
Q Liu, Y Bi, S Song, K Zhu, X Qiao, H Wang… - Stem Cell Research & …, 2023 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible
lung disease characterized by pulmonary fibrosis and lung dysfunction, ultimately leading to …
lung disease characterized by pulmonary fibrosis and lung dysfunction, ultimately leading to …
[HTML][HTML] Therapeutic potential of exosomes in pulmonary fibrosis
L Xie, Y Zeng - Frontiers in Pharmacology, 2020 - frontiersin.org
Pulmonary fibrosis is closely associated with the recruitment of fibroblasts from capillary
vessels with damaged endothelial cells, the epithelial mesenchymal transition (EMT) of type …
vessels with damaged endothelial cells, the epithelial mesenchymal transition (EMT) of type …
[HTML][HTML] Human umbilical cord mesenchymal stromal cell small extracellular vesicle transfer of microRNA-223-3p to lung epithelial cells attenuates inflammation in …
J Chen, S Ma, B Luo, H Hao, Y Li, H Yang… - Journal of …, 2023 - Springer
Background Acute lung injury (ALI), manifested as strong pulmonary inflammation and
alveolar epithelial damage, is a life-threatening disease with high morbidity and mortality …
alveolar epithelial damage, is a life-threatening disease with high morbidity and mortality …