Background It is known that the new membrane-bound estrogen receptor GPER-1 acts
suppressive in breast cancer cells and its expression decreases during disease …

For many patients, diabetes Mellitus and Malignancy are frequently encountered
comorbidities. Diabetes affects approximately 10.5% of the global population, while …

The G‐protein‐coupled estrogen receptor‐1 (GPER‐1), also known as GPR30, is a novel
estrogen receptor mediating estrogen receptor signaling in multiple cell types. The progress …

Estrogen classically drives lung cancer development via estrogen receptor β (ERβ).
However, fulvestrant, an anti-estrogen-based endocrine therapeutic treatment, shows limited …

Abstract 17β-Estradiol (estrogen), through receptor binding and activation, is required for
mammary gland development. Estrogen stimulates epithelial proliferation in the mammary …

G protein-coupled estrogen receptor (GPER) is known to play an important role in hormone-
associated cancers. G-1, a novel synthetic GPER agonist, has been reported to exhibit anti …

G protein-coupled estrogen receptor (GPER) is a novel estrogen-binding receptor involved
in many pathological conditions, including cancer. In this study, we investigated the effect of …

Cervical cancer is one of the most common gynaecological women cancer and suggested to
be modulated by estrogenic signals. G protein‐coupled receptor (GPER), a seven …

The role of 17β-estradiol (E2) in breast cancer development and tumor growth has
traditionally been attributed exclusively to the activation of estrogen receptor-α (ERα) …

GPER is a seven transmembrane G-protein-coupled estrogen receptor that mediates rapid
estrogen actions. Large volumes of data have revealed its association with …