Evaluation of the virucidal effects of rosmarinic acid against enterovirus 71 infection via in vitro and in vivo study
WY Lin, YJ Yu, TR Jinn - Virology journal, 2019 - Springer
Abstract Background Although enterovirus 71 (EV71) is an important public health threat,
especially in the Asia-Pacific region, there are still no effective drugs or vaccines to treat and …
especially in the Asia-Pacific region, there are still no effective drugs or vaccines to treat and …
Inhibition of enterovirus 71 replication and viral 3C protease by quercetin
C Yao, C Xi, K Hu, W Gao, X Cai, J Qin, S Lv, C Du… - Virology journal, 2018 - Springer
Abstract Background Enterovirus 71 (EV71) is one of the major causative agents of hand,
foot, and mouth disease (HFMD), which is sometimes associated with severe central …
foot, and mouth disease (HFMD), which is sometimes associated with severe central …
Anti-enterovirus 71 effects of chrysin and its phosphate ester
Enterovirus 71 (EV71) can cause severe disease and even lead to death in children, and an
effective antiviral drug is currently unavailable. The anti-EV71 effect of chrysin (5, 7 …
effective antiviral drug is currently unavailable. The anti-EV71 effect of chrysin (5, 7 …
Anti-enterovirus 71 activities of Melissa officinalis extract and its biologically active constituent rosmarinic acid
SG Chen, YL Leu, ML Cheng, SC Ting, CC Liu… - Scientific reports, 2017 - nature.com
Abstract Enterovirus 71 (EV71) infection is endemic in the Asia-Pacific region. No specific
antiviral drug has been available to treat EV71 infection. Melissa officinalis (MO) is a …
antiviral drug has been available to treat EV71 infection. Melissa officinalis (MO) is a …
Antiviral efficacy of flavonoids against enterovirus 71 infection in vitro and in newborn mice
W Dai, J Bi, F Li, S Wang, X Huang, X Meng, B Sun… - Viruses, 2019 - mdpi.com
Enterovirus 71 (EV71) infection is known to cause hand, foot, and mouth disease (HFMD),
which is associated with neurological complications; however, there is currently no effective …
which is associated with neurological complications; however, there is currently no effective …
Rheum emodin inhibits enterovirus 71 viral replication and affects the host cell cycle environment
T Zhong, LY Zhang, ZY Wang, Y Wang… - Acta Pharmacologica …, 2017 - nature.com
Abstract Human enterovirus 71 (EV71) is the primary causative agent of recent large-scale
outbreaks of hand, foot, and mouth disease (HFMD) in Asia. Currently, there are no drugs …
outbreaks of hand, foot, and mouth disease (HFMD) in Asia. Currently, there are no drugs …
Identification of luteolin as enterovirus 71 and coxsackievirus A16 inhibitors through reporter viruses and cell viability-based screening
Hand, foot and mouth disease (HFMD) is a common pediatric illness mainly caused by
infection with enterovirus 71 (EV71) and coxsackievirus A16 (CA16). The frequent HFMD …
infection with enterovirus 71 (EV71) and coxsackievirus A16 (CA16). The frequent HFMD …
Luteoloside Acts as 3C Protease Inhibitor of Enterovirus 71 In Vitro
Z Cao, Y Ding, Z Ke, L Cao, N Li, G Ding, Z Wang… - PLoS …, 2016 - journals.plos.org
Luteoloside is a member of the flavonoids family that exhibits several bioactivities including
anti-microbial and anti-cancer activities. However, the antiviral activity of luteoloside against …
anti-microbial and anti-cancer activities. However, the antiviral activity of luteoloside against …
Harmine, a small molecule derived from natural sources, inhibits enterovirus 71 replication by targeting NF-κB pathway
D Chen, X Tian, X Zou, S Xu, H Wang, N Zheng… - International …, 2018 - Elsevier
Abstract Enterovirus 71 (EV71) infection of young children can cause neurological
manifestations, which is mainly responsible for the fatality. Although a vaccine is recently …
manifestations, which is mainly responsible for the fatality. Although a vaccine is recently …
Resveratrol inhibits enterovirus 71 replication and pro-inflammatory cytokine secretion in rhabdosarcoma cells through blocking IKKs/NF-κB signaling pathway
L Zhang, Y Li, Z Gu, Y Wang, M Shi, Y Ji, J Sun, X Xu… - PloS one, 2015 - journals.plos.org
Polydatin and resveratrol, as major active components in Polygonum cuspidatum, have anti-
inflammatory, antioxidant and antitumor functions. However, the effect and mechanism of …
inflammatory, antioxidant and antitumor functions. However, the effect and mechanism of …