[HTML][HTML] The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery

AE van de Logt, M Fresquet, JF Wetzels, P Brenchley - Kidney international, 2019 - Elsevier
The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary
target in membranous nephropathy (MN) greatly advanced basic and clinical research …

Epitope spreading of autoantibody response to PLA2R associates with poor prognosis in membranous nephropathy

B Seitz-Polski, G Dolla, C Payré… - Journal of the …, 2016 - journals.lww.com
The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …

Detection of PLA2R autoantibodies before the diagnosis of membranous nephropathy

PD Burbelo, M Joshi, A Chaturvedi… - Journal of the …, 2020 - journals.lww.com
Background Circulating serum autoantibodies against the M-type phospholipase A2
receptor (PLA2R-AB) are a key biomarker in the diagnosis and monitoring of primary …

[HTML][HTML] Anti-PLA2R antibodies measured by ELISA predict long-term outcome in a prevalent population of patients with idiopathic membranous nephropathy

D Kanigicherla, J Gummadova, EA McKenzie… - Kidney international, 2013 - Elsevier
Antibodies to the phospholipase A2 receptor 1 (PLA2R1) have been reported in 70% of
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …

Anti-PLA2R antibodies as a prognostic factor in PLA2R-related membranous nephropathy

SA Timmermans, MA Abdul Hamid… - American journal of …, 2015 - karger.com
Background: The natural course of idiopathic membranous nephropathy (MN) varies, as it is
known through favorable outcomes in most patients. However, one third of patients with …

Antiphospholipase A2 receptor antibody titer and subclass in idiopathic membranous nephropathy

JM Hofstra, H Debiec, CD Short, T Pellé… - Journal of the …, 2012 - journals.lww.com
The phospholipase A 2 receptor (PLA 2 R) is the major target antigen in idiopathic
membranous nephropathy. The technique for measuring antibodies against PLA 2 R and …

Diagnostic specificity of autoantibodies to M-type phospholipase A2 receptor (PLA2R) in differentiating idiopathic membranous nephropathy (IMN) from secondary …

A Radice, F Pieruzzi, B Trezzi, G Ghiggeri… - Journal of …, 2018 - Springer
Autoantibody against phospholipase A2 receptor (anti-PLA2R) is a sensitive and specific
biomarker of idiopathic membranous nephropathy (iMN), being found in approximately 70 …

Clinical relevance of domain-specific phospholipase A2 receptor 1 antibody levels in patients with membranous nephropathy

L Reinhard, G Zahner, S Menzel… - Journal of the …, 2020 - journals.lww.com
Background Antibodies against phospholipase A 2 receptor 1 (PLA 2 R1) are found in 80%
of patients with membranous nephropathy, and previous studies described three …

Evaluation of anti-PLA2R1 as measured by a novel ELISA in patients with idiopathic membranous nephropathy: a cohort study

SA Timmermans, JGMC Damoiseaux… - American journal of …, 2014 - academic.oup.com
Objectives: Autoantibodies against the M-type phospholipase A2 receptor 1 (anti-PLA2R1)
have been demonstrated to be very specific for idiopathic membranous nephropathy (MN) …

Clinical usefulness of autoantibodies to M-type phospholipase A2 receptor (PLA2R) for monitoring disease activity in idiopathic membranous nephropathy (IMN)

A Radice, B Trezzi, U Maggiore, F Pregnolato… - Autoimmunity …, 2016 - Elsevier
Autoantibodies to M-type phospholipase A2 receptor (PLA2R) are specific markers of
idiopathic membranous nephropathy (IMN). They can differentiate IMN from other …