Streptococcus pneumoniae is a highly impactful bacterial pathogen on a global scale. The
principal pneumococcal virulence factor and target of effective vaccines is its polysaccharide …

The polysaccharide capsule is a key virulence factor of Streptococcus pneumoniae. There
are numerous epidemiologically important pneumococcal capsular serotypes, and recent …

The polysaccharide capsule is a major virulence factor of Streptococcus pneumoniae and
the target of all currently licensed pneumococcal vaccines. At present, there are 92 …

Streptococcus pneumoniae strains which fail to produce a polysaccharide capsule are
commonly isolated from carriage and disease contexts. Here we use a multilocus approach …

Streptococcus pneumoniae (the pneumococcus) is a human pathogen responsible for a
spectrum of diseases such as pneumonia, sepsis, and meningitis. The capsule is the major …

We performed culture-based and PCR-based tests for pneumococcal identification and
serotyping from carriage specimens collected in rural and urban Kenya. Nasopharyngeal …

Genetic studies of serogroup 6 isolates of Streptococcus pneumoniae identified putative
serotype 6E. Although its capsular polysaccharide structure has not been elucidated …

The major virulence factor of the pneumococcus, and target for conjugate vaccines, is the
polysaccharide capsule, which is usually encoded by the highly variable cps locus. Serotype …

The prevalence of Streptococcus pneumoniae serotype 6C, a recently recognized serotype
that cross-reacts serologically with serotype 6A, was investigated. Isolates of serotype 6A in …

Streptococcus pneumoniae expressing serogroup 6 capsules frequently causes
pneumococcal infections and the evolutionary origins of the serogroup 6 strains have been …