Using Solid-State NMR To Monitor the Molecular Consequences of Cryptococcus neoformans Melanization with Different Catecholamine Precursors
Melanins are a class of natural pigments associated with a wide range of biological
functions, including microbial virulence, energy transduction, and protection against solar …
functions, including microbial virulence, energy transduction, and protection against solar …
[HTML][HTML] Solid-state NMR reveals the carbon-based molecular architecture of Cryptococcus neoformans fungal eumelanins in the cell wall
S Chatterjee, R Prados-Rosales, B Itin… - Journal of Biological …, 2015 - ASBMB
Melanin pigments protect against both ionizing radiation and free radicals and have
potential soil remediation capabilities. Eumelanins produced by pathogenic Cryptococcus …
potential soil remediation capabilities. Eumelanins produced by pathogenic Cryptococcus …
Unlocking the Molecular Structure of Fungal Melanin Using 13C Biosynthetic Labeling and Solid-State NMR
S Tian, J Garcia-Rivera, B Yan, A Casadevall… - Biochemistry, 2003 - ACS Publications
Melanins are enigmatic pigments found in all biological kingdoms that are associated with a
variety of functions, including microbial virulence. Despite being ubiquitous in nature …
variety of functions, including microbial virulence. Despite being ubiquitous in nature …
Following fungal melanin biosynthesis with solid-state NMR: biopolymer molecular structures and possible connections to cell-wall polysaccharides
Melanins serve a variety of protective functions in plants and animals, but in fungi such as
Cryptococcus neoformans they are also associated with virulence. A recently developed …
Cryptococcus neoformans they are also associated with virulence. A recently developed …
[HTML][HTML] Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells
A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus
neoformans is the production of melanin pigments that are deposited into the cell wall and …
neoformans is the production of melanin pigments that are deposited into the cell wall and …
[HTML][HTML] The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans
Melanins are synthesized macromolecules that are found in all biological kingdoms. These
pigments have a myriad of roles that range from microbial virulence to key components of …
pigments have a myriad of roles that range from microbial virulence to key components of …
Capsule and melanin synthesis in Cryptococcus neoformans
DC McFadden, A Casadevall - Medical Mycology, 2001 - Taylor & Francis
Melanization is a property that is shared among several human pathogenic fungi, whereas
encapsulation is a property unique to Cryptococcus neoformans. Focusing on C …
encapsulation is a property unique to Cryptococcus neoformans. Focusing on C …
The effect of L-DOPA on Cryptococcus neoformans growth and gene expression
HC Eisenman, SK Chow, KK Tsé, E McClelland… - Virulence, 2011 - Taylor & Francis
Cryptococcus neoformans is unusual among melanotic fungi in that it requires an
exogenous supply of precursor to synthesize melanin. C. neoformans melanizes during …
exogenous supply of precursor to synthesize melanin. C. neoformans melanizes during …
[HTML][HTML] Cryptococcus neoformans melanization incorporates multiple catecholamines to produce polytypic melanin
RP Baker, C Chrissian, RE Stark… - Journal of Biological …, 2022 - ASBMB
Melanin is a major virulence factor in pathogenic fungi that enhances the ability of fungal
cells to resist immune clearance. Cryptococcus neoformans is an important human …
cells to resist immune clearance. Cryptococcus neoformans is an important human …
[HTML][HTML] The melanization road more traveled by: Precursor substrate effects on melanin synthesis in cell-free and fungal cell systems
S Chatterjee, R Prados-Rosales, S Tan… - Journal of Biological …, 2018 - ASBMB
Natural brown–black eumelanin pigments confer structural coloration in animals and
potently block ionizing radiation and antifungal drugs. These functions also make them …
potently block ionizing radiation and antifungal drugs. These functions also make them …