Background: Sugammadex is a modified cyclodextrin that is being increasingly used in
anesthetic practice worldwide for the reversal of the aminosteroid neuromuscular blockers …

Study objective To evaluate the incidence of hypersensitivity and anaphylaxis after
administration of sugammadex. Design Retrospective analysis. Setting Sugammadex …

In this study, the published sugammadex-induced anaphylaxis reports were reviewed to
determine similarities in their presentation during anesthesia. PubMed was searched for …

We retrospectively investigated the incidence of potential sugammadex-induced
anaphylaxis at a single center in Japan over a period of 3 years. The overall incidence of …

Background We evaluated the incidence of hypersensitivity or anaphylaxis after repeated
single-dose sugammadex administration in non-anaesthetised adults. Methods In this …

Sugammadex is a drug used to reverse neuromuscular blockade induced by rocuronium or
vecuronium. It has not yet been approved by the Food and Drug Administration in the USA …

Background Sugammadex has a unique mechanism of action and is widely used because
of its safety and efficacy. A few recent reports have described allergic reactions to clinical …

Purpose of the review The γ-cyclodextrin sugammadex, chemically modified to encapsulate
the steroidal muscle relaxant rocuronium, was introduced into anesthesia as the first …

Editor—Anaphylaxis is a severe, life-threatening, generalized or systemic hypersensitivity
reaction mediated through immediate IgE-dependent mechanisms. When physicians …

Background We investigated potential for hypersensitivity reactions after repeated
sugammadex administration and explored the mechanism of hypersensitivity. Methods In …