Sex differences are a well-known phenomenon in Alzheimer's disease (AD), with women
having a higher risk for AD than men. Many AD mouse models display a similar sex …

Epidemiological studies indicate that women have a higher risk of Alzheimer's disease (AD)
even after adjustment for age. Though transgenic mouse models of AD develop AD-related …

Clinical studies have shown that female brains are more predisposed to neurodegenerative
diseases such as Alzheimer's disease (AD), but the cellular and molecular mechanisms …

The risk of Alzheimer's disease (AD) is higher in women than in men, a sex difference that
likely results from the effects of sex steroid hormones. To investigate this relationship, we first …

Female sex is a leading risk factor for developing Alzheimer's disease (AD). Sexual
dimorphism in AD is gaining attention as clinical data show that women are not only more …

Background: Nearly two-thirds of patients diagnosed with Alzheimer's disease (AD) are
female. In addition, female patients with AD have more significant cognitive impairment than …

Transgenic mice carrying both the human amyloid precursor protein (APP) with the Swedish
mutation and the presenilin-1 A246E mutation (APP/PS1 mice) develop Alzheimer's disease …

To determine if early cognitive/sensorimotor deficits exist in APPSW transgenic mice
overexpressing human amyloid precursor protein (APP), Tg+ and Tg− animals at both 3 and …

Women carry a higher burden of Alzheimer's disease (AD) compared to men, which is not
accounted entirely by differences in lifespan. To identify the mechanisms underlying this …

Introduction Epidemiological studies show that women have a higher prevalence of
Alzheimer's disease (AD) than men. Peripheral estrogen reduction during aging in women is …