Multiple sclerosis (MS) is a neurodegenerative disease that severely impairs quality of
life,(usually in midlife) and is also the most common cause of disability among young adults …

Background Cell-derived microparticles are secreted in response to cell damage or
dysfunction. Endothelial and platelet dysfunction are thought to contribute to the …

Multiple sclerosis (MS) is increasingly being viewed and studied not only as an immune-
mediated demyelinating and neurodegenerative disease of the human central nervous …

Monocyte migration through the disrupted cerebral endothelial cell (EC) junctions plays an
essential role in formation of multiple sclerosis (MS) demyelinating lesions. During …

Background Although multiple sclerosis (MS) is thought to represent an excessive and
inappropriate immune response to several central nervous system (CNS) autoantigens …

Objective: To assess endothelial dysfunction in patients with MS and to investigate whether
plasma from patients with MS induces endothelial cell dysfunction in vitro. Background …

Objectives We previously reported a correlation between levels of microparticles carrying
CD31 (PMP CD31+) and disease activity in MS. However, the effects of long term (12 month) …

Abstract Objective: Microvesicles (MVs) have been indicated as important mediators of
intercellular communication and are emerging as new biomarkers of tissue damage. Our …

Background Multiple sclerosis (MS), an autoimmune‐neurodegenerative disease, exhibits
features of neurovascular inflammation including endothelial activation and shedding of …

Background A correlation between plasma CD31+ endothelial microparticles (CD31+ EMP)
levels and clinical, as well as brain MRI activity, in multiple sclerosis (MS) patients has been …